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Ingredient Dictionary

ERGOTHIONEINE

Ergothioneine is a L-histidine derivative that is Nalpha,Nalpha,Nalpha-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 7 list it before the 1% line and 25 after it (usually 1% or less).

Products using this ingredient

12 of 32 confirmed · likeliest to carry enough first · See all 32

Definition

Ergothioneine is a L-histidine derivative that is Nalpha,Nalpha,Nalpha-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs. It has a role as an antioxidant, a chelator, a xenobiotic metabolite, a plant metabolite and a fungal metabolite. It is an amino-acid betaine, a sulfur-containing amino acid and a L-histidine derivative. It is a conjugate base of an ergothioneine(1+). It is a tautomer of an ergothioneine thione form.

Source: PubChem

US FDA substance register · UNII BDZ3DQM98W · registered name ERGOTHIONEINE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Ergothioneine is the heterocyclic compound that conforms to the formula

Cosmetic roles

Skin conditioning not covered aboveSKIN CONDITIONING - MISCELLANEOUSSlows spoilage by oxygenANTIOXIDANT
More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name エルゴチオネイン: 本品は、次の化学式で表される複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

ERGOTHIONEINEINCI에르고티오네인Korean label name (MFDS standard)エルゴチオネインJapanese labelling name
CAS No.chemical registry number
497-30-3
EC No.EU chemical inventory number
207-843-5
DTXSIDUS EPA chemical ID
DTXSID901020082
DTXCIDUS EPA compound ID
DTXCID901477922
IUPAC
(2S)-3-(2-Sulfanylidene-2,3-dihydro-1H-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate
Molecular formula
C9H15N3O2S
Molecular weight
229.3 g/mol

Measured properties

Appearance
Solid

Values measured on the substance itself, not a specification for a commercial raw material.

Source: PubChem

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Antioxidant2

Source: US EPA CompTox dashboard

Related literature

Linked databases 16