Ingredient Dictionary

ERUCAMIDE

Erucamide is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.

Definition

Erucamide is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia. It is commonly used as a slip additive in the plastic manufacturing industry. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a mammalian metabolite, a plant metabolite, a human metabolite and a rat metabolite. It is functionally related to an erucic acid.

Source: PubChem

US FDA substance register · UNII 0V89VY25BN · registered name ERUCAMIDE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adjusts thicknessVISCOSITY CONTROLLINGMakes a clear formula opaqueOPACIFYING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

ERUCAMIDEINCI에루카마이드Korean label name (MFDS standard)13-Docosenamide, (Z)-Synonym

CAS No.chemical registry number: 3061-72-1
CAS No.chemical registry number: 112-84-5
EC No.EU chemical inventory number: 204-009-2 / 931-599-5
EC No.EU chemical inventory number: 931-599-5
EC No.EU chemical inventory number: 204-009-2
DTXSIDUS EPA chemical ID: DTXSID4026929
DTXCIDUS EPA compound ID: DTXCID606929

IUPAC: (13Z)-Docos-13-enamide
Molecular formula: C22H43NO
Molecular weight: 337.592 g/mol

Measured properties

Appearance: Dry Powder, Large Crystals, Other Solid, CBI · Solid, [Hawley] Off-white beads with a fatty odor, [MSDSonline]
Melting point: 75-80 °C
Solubility: SOL IN ISOPROPANOL, SLIGHTLY SOL IN ALCOHOL, ACETONE
Melting/freezing point: 77.5 ℃
Initial boiling point and range: 460~488 ℃
Flash point: 221~261 ℃ (calc.)
Vapour pressure: 0.00000000582 ㎜Hg (@ 25 ℃, est.)
Water solubility: 0.2 ㎎/ℓ (@ 25 ℃, est.)
Vapour density: 11.65
Relative density: 0.908 (@ 20 ℃)
n-Octanol/water partition coefficient (Kow): 5.3 (est.)
Molecular weight: 337.56

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 38 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Anti-adhesive/cohesive19
Lubricating agent7
Processing aids not otherwise specified3
Anti-slip agent3
Hardener2
Anti-static agent1
Wetting agent (non-aqueous)1
Opacifer1

1 other uses

Viscosity modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low4

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) (2002) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) (2008)
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) (1984) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) (1984) according to