Erucamide is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.
定义
Erucamide is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia. It is commonly used as a slip additive in the plastic manufacturing industry. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a mammalian metabolite, a plant metabolite, a human metabolite and a rat metabolite. It is functionally related to an erucic acid.
来源: PubChem
美国FDA 物质登记 · UNII 0V89VY25BN · 登记名称 ERUCAMIDE · 单一化学物质
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 3061-72-1
- CAS No.化学物质登记号
- 112-84-5
- EC No.欧盟化学品目录编号
- 931-599-5
- EC No.欧盟化学品目录编号
- 204-009-2
- DTXSID美国EPA化学品编号
- DTXSID4026929
- DTXCID美国EPA化合物编号
- DTXCID606929
- IUPAC
- (13Z)-Docos-13-enamide
- 分子式
- C22H43NO
- 分子量
- 337.592 g/mol
实测物性
- 性状
- Dry Powder, Large Crystals, Other Solid, CBI · Solid, [Hawley] Off-white beads with a fatty odor, [MSDSonline]
- 熔点
- 75-80 °C
- 溶解性
- SOL IN ISOPROPANOL, SLIGHTLY SOL IN ALCOHOL, ACETONE
- 熔点/凝固点
- 77.5 ℃
- 初沸点和沸程
- 460~488 ℃
- 闪点
- 221~261 ℃ (计算值)
- 蒸气压
- 0.00000000582 ㎜Hg (@ 25 ℃, 估算值)
- 溶解度
- 0.2 ㎎/ℓ (@ 25 ℃, 估算值)
- 蒸气密度
- 11.65
- 比重
- 0.908 (@ 20 ℃)
- 正辛醇/水分配系数(Kow)
- 5.3 (估算值)
- 分子量
- 337.56
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 38 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Anti-adhesive/cohesive19
- Lubricating agent7
- Processing aids not otherwise specified3
- Anti-slip agent3
- Hardener2
- Anti-static agent1
- Wetting agent (non-aqueous)1
- Opacifer1
其余用途 1 项
- Viscosity modifier1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 4 项、眼部试验 2 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 6 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) (2002) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) (2008) - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) (1984) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) (1984) according to
来源: 美国EPA CompTox
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