Ethanolamine is a member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.
How much products actually contain
No product states its amount yet.
Of the products containing it, 13 list it before the 1% line and 2 after it (usually 1% or less).
Products using this ingredient
12 of 15 confirmed · likeliest to carry enough first · See all 15
MiseensceneAll New Easy & Quick Cream Hair Dye (Gray Coverage/Root Touch-Up)
MiseensceneAll New Easy & Quick Bubble Hair Dye (Gray Coverage)
DASHUDASHU Color Fast Change Hair Dye 120g (3 Types)
ANAZESelf Touch-Up Color Kit B01 Brown
MOREMO KeratinMoremo Keratin Low-Damage Hair Color Gray Coverage & Fashion Color 2 Types
JSOOPJSOOP Style J for Men Self Down Perm 120ml
PARKJUN BEAUTY LABSalon Root Cover Hair Color 300ml Jumbo (4 Colors)
MOREMO KeratinLow-Damage Hair Color Matte Deep Brown
MOREMO KeratinLow-Damage Hair Color Ash Gray
MOREMO KeratinRoot Touch-Up Magic Straight
SEVENPMReal Comb Magic Perm
SEVENPMReal Comb Down Perm
Definition
Ethanolamine is a member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol. It has a role as a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a primary alcohol, a member of ethanolamines and a primary amine. It is a conjugate base of an ethanolaminium(1+).
Source: PubChem
US FDA substance register · UNII 5KV86114PT · registered name Ethanolamine · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
- Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.
ASEAN
- Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
- Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers
European Union
- Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
- Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
Source: MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Danger · H332 (category 4) · H314 (category 1B) · H412 (category 3) · +3 more
Restriction III/61 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Ethanolamine and Ethanolamine Salts as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name エタノールアミン: 本品は、次の化学式で表されるアルカノールアミンである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 141-43-5
- EC No.EU chemical inventory number
- 205-483-3
- DTXSIDUS EPA chemical ID
- DTXSID6022000
- DTXCIDUS EPA compound ID
- DTXCID202000
- IUPAC
- 2-Aminoethan-1-ol
- Molecular formula
- C2H7NO
- Molecular weight
- 61.084 g/mol
Measured properties
- Appearance
- Ethanolamine appears as a clear colorless liquid with an odor resembling that of ammonia. Flash point 185 °F. May attack copper, brass, and rubber. Corrosive to tissue. Moderately toxic. Produces toxic oxides of nitrogen during combustion. · Liquid, Other Solid, CBI, Large Crystals
- Odour
- Unpleasant, ammonia-like
- Boiling point
- 338 °F at 760 mmHg (NTP, 1992) · 171 °C
- Melting point
- 50.5 °F (NTP, 1992) · 10.5 °C
- Solubility
- greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) · 1000000 mg/L
- Density
- 1.016 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.0180 g/cu cm at 20 °C
- Stability
- Chemical stability: Absorbs carbon dioxide (CO2) from air. Stable under recommended storage conditions.
- Colour
- colourless
- pH
- 12.1
- Melting/freezing point
- 10 ℃
- Initial boiling point and range
- 171 ℃
- Flash point
- 92.5 ℃
- Upper/lower flammability or explosive limits
- 17 / 5.5 %
- Vapour pressure
- 53 ㎩(20℃)
- Water solubility
- 100 g/100㎖(25℃)
- Relative density
- 1.02
- n-Octanol/water partition coefficient (Kow)
- -1.31
- Auto-ignition temperature
- 410 ℃(at 1013 hPa)
- Viscosity
- 18.95 cP(25℃)
- Molecular weight
- 61.08
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 429 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent216
- Chelating agent60
- Solvent50
- Processing aids not otherwise specified49
- Defoamer8
- Cleaning agent7
- Surfactant (surface active agent)6
- Intermediate4
21 other uses
- Stabilizing agent3
- Corrosion inhibitor3
- Dye2
- Preservative2
- Surface modifier2
- Emulsifier2
- Catalyst1
- Monomers1
- Etching agent1
- Flotation agent1
- Humectant1
- Hardener1
- Sizing agent1
- Anti-freeze agent1
- Soil amendments1
- Pharmaceutical (EPA)1
- Fragrance1
- Semiconductor and photovoltaic agent1
- Absorbent1
- Dispersing agent1
- Binder1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 10 studies
- Skin Corr. 1B
Skin Irritation · Authoritative - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 1
Skin Sensitization · Screening - Sh
Skin Sensitization · Authoritative - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to other guideline: Guinea Pig Maximisation Test - Category 8.3A (Category 1)
Eye Irritation · Read Across - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Dose-Dependent Physiological, Genotoxic and Histological Effects of Ethanolamine in A Plant Bioindicator System (Allium cepa L.) · 2026
- Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva. · 2021
- Safety Assessment of Ethanolamine and Ethanolamine Salts as Used in Cosmetics · 2015
- Infantile Hemangioma Treated with Dermal Injection of Ethanolamine Oleate · 2010
- Treatment of venous malformations with ethanolamine oleate. · 2008
Linked databases 22
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese