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成分词典

成分词典

ETHANOLAMINE

Ethanolamine is a member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.

分子结构

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中,13 款将其列在 1% 线之前,2 款列在之后(通常不超过 1%)。

含有此成分的产品

已确认 15 款中的 12 款 · 按含量充足程度排序 · 查看全部 15 款

定义

Ethanolamine is a member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol. It has a role as a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a primary alcohol, a member of ethanolamines and a primary amine. It is a conjugate base of an ethanolaminium(1+).

来源: PubChem

美国FDA 物质登记 · UNII 5KV86114PT · 登记名称 Ethanolamine · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

化妆品中的作用

稳定 pHBUFFERING

安全与法规参考

限用·禁用
韩国 · 中国

来源: 韩国食药处 化妆品法规信息

阿根廷 · 巴西

  • Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
  • Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.

东盟

  • Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
  • Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers

欧盟

  • Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
  • Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

来源: 韩国食药处 化妆品法规信息

韩国有毒物质 GHS 分类: 危险 · H332 (第4类) · H314 (第1B类) · H412 (第3类) · 另有 3 项

来源: 韩国有毒物质 GHS 信息(环境公团)

Restriction III/61 · Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Safety Assessment of Ethanolamine and Ethanolamine Salts as Used in Cosmetics

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

官方标示名称和定义

日本化妆品工业联合会标示名称 エタノールアミン: 本品は、次の化学式で表されるアルカノールアミンである。

来源: 日本化妆品工业联合会标示名称

别名和识别信息

ETHANOLAMINEINCI에탄올아민韩国标示名称(食药处标准名)Ethanol, 2-amino-同义名エタノールアミン日本标示名称
CAS No.化学物质登记号
141-43-5
EC No.欧盟化学品目录编号
205-483-3
DTXSID美国EPA化学品编号
DTXSID6022000
DTXCID美国EPA化合物编号
DTXCID202000
IUPAC
2-Aminoethan-1-ol
分子式
C2H7NO
分子量
61.084 g/mol

实测物性

性状
Ethanolamine appears as a clear colorless liquid with an odor resembling that of ammonia. Flash point 185 °F. May attack copper, brass, and rubber. Corrosive to tissue. Moderately toxic. Produces toxic oxides of nitrogen during combustion. · Liquid, Other Solid, CBI, Large Crystals
气味
Unpleasant, ammonia-like
沸点
338 °F at 760 mmHg (NTP, 1992) · 171 °C
熔点
50.5 °F (NTP, 1992) · 10.5 °C
溶解性
greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) · 1000000 mg/L
密度
1.016 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.0180 g/cu cm at 20 °C
稳定性
Chemical stability: Absorbs carbon dioxide (CO2) from air. Stable under recommended storage conditions.
颜色
无色
pH
12.1
熔点/凝固点
10 ℃
初沸点和沸程
171 ℃
闪点
92.5 ℃
燃烧或爆炸范围上限/下限
17 / 5.5 %
蒸气压
53 ㎩(20℃)
溶解度
100 g/100㎖(25℃)
比重
1.02
正辛醇/水分配系数(Kow)
-1.31
自燃温度
410 ℃(at 1013 hPa)
黏度
18.95 cP(25℃)
分子量
61.08

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: PubChem · 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 429 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • pH regulating agent216
  • Chelating agent60
  • Solvent50
  • Processing aids not otherwise specified49
  • Defoamer8
  • Cleaning agent7
  • Surfactant (surface active agent)6
  • Intermediate4
其余用途 21 项
  • Stabilizing agent3
  • Corrosion inhibitor3
  • Dye2
  • Preservative2
  • Surface modifier2
  • Emulsifier2
  • Catalyst1
  • Monomers1
  • Etching agent1
  • Flotation agent1
  • Humectant1
  • Hardener1
  • Sizing agent1
  • Anti-freeze agent1
  • Soil amendments1
  • Pharmaceutical (EPA)1
  • Fragrance1
  • Semiconductor and photovoltaic agent1
  • Absorbent1
  • Dispersing agent1
  • Binder1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 7 项、眼部试验 3 项。

归类为刺激性高1 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 10 项试验
  • Skin Corr. 1B
    Skin Irritation · Authoritative
  • Category 8.2C (Category 1C)
    Skin Irritation · Read Across
  • Corrosive
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Category 1
    Skin Sensitization · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Skin corrosion/irritation - Category 1
    Skin Irritation · Screening
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to other guideline: Guinea Pig Maximisation Test
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to

来源: 美国EPA CompTox

相关文献

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