Ethinylestradiol can cause cancer according to an independent committee of scientific and health experts.
Definition
Ethinylestradiol can cause cancer according to an independent committee of scientific and health experts.
Source: PubChem
US FDA substance register · UNII 423D2T571U · registered name ETHINYL ESTRADIOL · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Canada · Taiwan
- Restricted or banned
- Canada · Japan · Taiwan
Source: Health Canada Cosmetic Ingredient Hotlist · Taiwan FDA cosmetic ingredients · MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics
Restriction II/260
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name エチニルエストラジオール: 本品は、卵胞ホルモン誘導体であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 57-63-6
- EC No.EU chemical inventory number
- 200-342-2
- DTXSIDUS EPA chemical ID
- DTXSID5020576
- DTXCIDUS EPA compound ID
- DTXCID70576
- IUPAC
- 17alpha-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol
- Molecular formula
- C20H24O2
- Molecular weight
- 296.41 g/mol
Measured properties
- Appearance
- Ethinylestradiol is a fine white to creamy white powder. A synthetic steroid. Used in combination with progestogen as an oral contraceptive. · Solid
- Odour
- Odorless · odourless
- Melting point
- 288 to 295 °F (NTP, 1992) · 142-144
- Solubility
- less than 1 mg/mL at 70 °F (NTP, 1992) · 11.3 mg/L (at 27 °C)
- Colour
- white
- Melting/freezing point
- 183 ℃
- Vapour pressure
- 0.00000000267 ㎜Hg (@ 25 ℃, est.)
- Water solubility
- 11.3 ㎎/ℓ (27℃)
- Vapour density
- 10.23
- n-Octanol/water partition coefficient (Kow)
- 4.77 (est.)
- Molecular weight
- 296.41
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Recent investigations on the impact of levonorgestrel and 17β-ethinylestradiol on melanoma · 2025
- FORMULATION AND DEVELOPMENT OF TRANSDERMAL DRUG DELIVERY SYSTEM OF ETHINYLESTRADIOL AND TESTOSTERONE: IN VITRO EVALUATION · 2019
- EFFECT OF HYDROPHILIC AND HYDROPHOBIC POLYMER MATRIX ON THE TRANSDERMAL DRUG DELIVERY OF ETHINYLESTRADIOL AND MEDROXYPROGESTERONE ACETATE · 2019
- Phototoxic reaction to a combined oral contraceptive (levonorgestrel/ethinylestradiol) · 2017
- Evaluation of Risk-Minimization Activities for Cyproterone Acetate 2 mg/Ethinylestradiol 35 µg: A Cross-Sectional Physician Survey · 2017
Linked databases 20
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese