Definition
US FDA substance register · UNII W5EIM81UBX · registered name DIETHYLENE GLYCOL MONOETHYL ETHER ACETATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 酢酸エトキシジグリコール: 本品は、酢酸とエトキシジグリコール（＊）のエステルであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 112-15-2
- EC No.EU chemical inventory number
- 203-940-1
- DTXSIDUS EPA chemical ID
- DTXSID6026905
- DTXCIDUS EPA compound ID
- DTXCID406905
- IUPAC
- 2-(2-Ethoxyethoxy)ethyl acetate
- Molecular formula
- C8H16O4
- Molecular weight
- 176.212 g/mol
Measured properties
- Appearance
- Diethylene glycol ethyl ether acetate is a colorless liquid. (USCG, 1999) · Liquid
- Odour
- Characteristic: quality: sweet, hedonic tone: pleasant to unpleasant.
- Boiling point
- 423.32 °F at 760 mmHg (USCG, 1999) · 218.5 °C
- Melting point
- -13 °F (USCG, 1999) · -25 °C
- Solubility
- Miscible with water, alcohol, ether, most oils · Very soluble in acetone, ethyl ether, ethanol
- Density
- 1.0114 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.0096 g/cu cm at 20 °C
- Stability
- Very low volatility
- Viscosity
- 0.0279 cP at 20 °C · 0.0279 cP (@ 20 ℃)
- Colour
- colourless
- Melting/freezing point
- -25 ℃
- Initial boiling point and range
- 218.5 ℃
- Flash point
- 112 ℃(c.c., @ 960 hPa)
- Flammability (solid, gas)
- combustible
- Upper/lower flammability or explosive limits
- 0.76 / 5.0 %
- Vapour pressure
- 0.0989 ㎜Hg (@ 20 ℃)
- Water solubility
- 1000000 ㎎/ℓ (@ 20 ℃)
- Vapour density
- 6.07
- Relative density
- 1.0096 (HSDB)
- n-Octanol/water partition coefficient (Kow)
- 0.32 (est.)
- Auto-ignition temperature
- 295 ℃
- Molecular weight
- 176.21
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent6
- Film former2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted in 1981 according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted 1981 - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted in 1987 according to - Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata