Ethyl 3,4-dihydroxybenzoate is an ethyl ester resulting from the formal condensation of the carboxy group of 3,4-dihydroxybenzoic acid with ethanol.
定义
Ethyl 3,4-dihydroxybenzoate is an ethyl ester resulting from the formal condensation of the carboxy group of 3,4-dihydroxybenzoic acid with ethanol. It is the anti-oxidative component of peanut seed testa. It has a role as an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor, an antioxidant, an antibacterial agent, an apoptosis inducer and a plant metabolite. It is an ethyl ester and a member of catechols. It is functionally related to a 3,4-dihydroxybenzoic acid.
来源: PubChem
美国FDA 物质登记 · UNII 4YGJ96WTBG · 登记名称 ETHYL PROTOCATECHUATE · 单一化学物质
Ethyl 3,4-Dihydroxybenzoate is the ethyl ester of 3,4-Dihydroxybenzoic Acid that conforms to the formula
化妆品中的作用
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 3943-89-3
- EC No.欧盟化学品目录编号
- 223-529-0
- DTXSID美国EPA化学品编号
- DTXSID2057732
- DTXCID美国EPA化合物编号
- DTXCID3031521
- IUPAC
- Ethyl 3,4-dihydroxybenzoate
- 分子式
- C9H10O4
- 分子量
- 182.175 g/mol
实测物性
- 性状
- 固体
- 熔点/凝固点
- 44 ℃
- 初沸点和沸程
- 441.82 ℃
- 蒸气压
- 0 ㎩ (20°C)
- 溶解度
- (&, lt, 20 μg @ 20°C)
- 蒸气密度
- 14.17777010700725
- 比重
- 0.917 (g/cm³ at 20°C)
- 分子量
- 410.73
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
刺激与致敏试验记录
记录有皮肤试验 2 项、眼部试验 0 项。
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 2 项试验
- SkinSens1
Skin Sensitization · QSAR Predicted - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation)
来源: 美国EPA CompTox
相关文献
- Functional role of type VI collagen during early feather development of the chicken embryo in vitro · 2005
- Inhibition of prolyl hydroxylation during collagen biosynthesis in human skin fibroblast cultures by ethyl 3,4-dihydroxybenzoate. · 1987
- Reduction of collagen production in keloid fibroblast cultures by ethyl-3,4-dihydroxybenzoate. Inhibition of prolyl hydroxylase activity as a mechanism of action. · 1987