Ethyl Acrylate can cause cancer according to an independent committee of scientific and health experts.
Definition
Ethyl Acrylate can cause cancer according to an independent committee of scientific and health experts.
Source: PubChem
US FDA substance register · UNII 71E6178C9T · registered name Ethyl acrylate · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · China · European Union · International fragrance standard (IFRA) · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · IFRA fragrance standards · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Danger · H319 (category 2) · H317 (category 1) · H412 (category 3) · +6 more
EU Cosmetics Regulation, Annex II (prohibited substances), entry 435
Restriction II/435 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アクリル酸エチル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 140-88-5
- EC No.EU chemical inventory number
- 205-438-8
- DTXSIDUS EPA chemical ID
- DTXSID4020583
- DTXCIDUS EPA compound ID
- DTXCID00583
- IUPAC
- Ethyl prop-2-enoate
- Molecular formula
- C5H8O2
- Molecular weight
- 100.117 g/mol
Measured properties
- Appearance
- Ethyl acrylate, stabilized appears as a clear colorless liquid with an acrid odor. Flash point 60 °F. May polymerize exothermically if heated or contaminated. If the polymerization takes place inside a container, the container may rupture violently. Auto ignition temperature 721 °F (383 °C) (NTP). Less dense than water. Vapors heavier than air. Used to make paints and plastics. · Liquid, Large Crystals
- Odour
- Acrid penetrating odor · Sour, pungent, hot plastic odor
- Boiling point
- 211.6 °F at 760 mmHg (NTP, 1992) · 99.4 °C
- Melting point
- -96.2 °F (NTP, 1992) · -71.2 °C
- Solubility
- 10 to 50 mg/mL at 70 °F (NTP, 1992) · Slightly soluble in dimethyl sulfoxide, soluble in chloroform, miscible in ethanol, ethyl ether
- Density
- 0.923 at 68 °F (USCG, 1999) - Less dense than water, will float
- Colour
- colourless
- Melting/freezing point
- -71 ℃
- Initial boiling point and range
- 99 ℃
- Flash point
- 9 ℃
- Upper/lower flammability or explosive limits
- 14 / 1.4 %
- Vapour pressure
- 3.8 ㎪(20℃)
- Water solubility
- 1.5 g/100㎖(20 ℃)
- Vapour density
- 3.45
- Relative density
- 0.92
- n-Octanol/water partition coefficient (Kow)
- 1.32
- Auto-ignition temperature
- 345 ℃
- Viscosity
- 0.54 cP
- Molecular weight
- 100.11582
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 18 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Monomers4
- Surfactant (surface active agent)2
- Flavouring and nutrient2
- Binder1
- Plasticizer1
- Cleaning agent1
- Fragrance1
- Elasticizer1
5 other uses
- Degradant/impurity (EPA)1
- Solvent1
- Processing aids not otherwise specified1
- Catalyst1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
11 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 14 studies
- Sh
Skin Sensitization · Authoritative - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Skin sensitization - Category 1
Skin Sensitization · Screening - Category 2
Skin Irritation · Screening - Category 1
Skin Sensitization · Screening - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 6.3A (Category 2)
Skin Irritation · Read Across - Skin Sens. 1
Skin Sensitization · Authoritative - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Skin Irrit. 2
Skin Irritation · Authoritative - Eye Irrit. 2
Eye Irritation · Authoritative - Category 2A
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Occupational contact dermatitis in a manicurist · 2019
- n‐Butylacrylat [MAK Value Documentation in German language, 2017] · 2017
- Proteomic analysis of haptenation by skin sensitisers: Diphencyprone and ethyl acrylate. · 2020
- Comparative analysis of skin sensitization potency of acrylates (methyl acrylate, ethyl acrylate, butyl acrylate, and ethylhexyl acrylate) using the local lymph node assay · 2007
- Cotton fibers encapsulated with homo- and block copolymers: synthesis by the atom transfer radical polymerization grafting-from technique and solid-state NMR dynamic investigations. · 2007
Linked databases 26
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- IARC carcinogen classification
- IFRA fragrance standards
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · English · Japanese · Chinese