Ingredient Dictionary

ETHYL BUTYRATE

Ethyl butyrate is a butyrate ester resulting from the formal condensation of the hydroxy group of ethanol with the carboxy group of butyric acid.

Definition

Ethyl butyrate is a butyrate ester resulting from the formal condensation of the hydroxy group of ethanol with the carboxy group of butyric acid. It has a role as a plant metabolite. It is functionally related to an ethanol.

Source: PubChem

US FDA substance register · UNII UFD2LZ005D · registered name Ethyl butyrate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

ETHYL BUTYRATEINCI에틸부티레이트Korean label name (MFDS standard)Butanoic acid, ethyl esterSynonym

CAS No.chemical registry number: 105-54-4
EC No.EU chemical inventory number: 203-306-4
DTXSIDUS EPA chemical ID: DTXSID6040111
DTXCIDUS EPA compound ID: DTXCID4020111

IUPAC: Ethyl butanoate
Molecular formula: C6H12O2
Molecular weight: 116.16 g/mol

Measured properties

Appearance: Ethyl butyrate appears as a clear colorless liquid with a pineapple-like odor. Flash point 78 °F. Less dense than water and insoluble in water. Vapors heavier than air. · CBI, Liquid
Odour: Pineapple odor
Boiling point: 250 °F at 760 mmHg (USCG, 1999) · 120-121 °C
Melting point: -135 °F (USCG, 1999) · -97 °C
Solubility: In water, 4.9X10+3 mg/L at 20 °C · Soluble in about 150 parts water
Density: 0.879 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.8735 g/cu cm at 25 °C
Stability: Chemical stability: Stable under recommended storage conditions.
Viscosity: 0.639 mPa.s at 25 °C · 0.56 cP (40 C)
pH: Acid value: 1.0 (max)
Colour: colourless
Odour threshold: 0.015 ppm
Melting/freezing point: -101~-93 ℃
Initial boiling point and range: 118~122 ℃
Flash point: 24 ℃
Upper/lower flammability or explosive limits: 7.7 / 1.3 %
Vapour pressure: 12.8 ㎜Hg (20℃)
Water solubility: 4900 ㎎/ℓ
Vapour density: 4.0
Relative density: 0.8785 (at 20℃)
n-Octanol/water partition coefficient (Kow): 1.85 ((est.))
Auto-ignition temperature: 463 ℃
Molecular weight: 116.16

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 195 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance186
Flavouring and nutrient4
Solvent3
Plasticizer2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 3 eye studies are on record.

Classed as highly irritating1Classed as moderate1Classed as low3

The studies disagree (the most common conclusion covers 20%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below
Category 2
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: see Principles below
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: OECD 402 according to
Severe Irritation
skin irritation: in vivo · Screening · other guideline: as below according to
Category 6.3B (Category 3)
Skin Irritation · Read Across
Classification not possible
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below equivalent or similar to