Diethyl ether is an ether in which the oxygen atom is linked to two ethyl groups.
定義
Diethyl ether is an ether in which the oxygen atom is linked to two ethyl groups. It has a role as an inhalation anaesthetic, a non-polar solvent and a refrigerant. It is a volatile organic compound and an ether.
出典: PubChem
米国FDA 物質登録 · UNII 0F5N573A2Y · 登録名 Ether · 単一の化学物質
化粧品での役割
安全性・規制情報
韓国の有害物質GHS分類なし · 既存化学物質
Other restriction: ban substances that deplete the ozone layer
出典: EU CosIng 成分リスト
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 60-29-7
- EC No.EU化学物質目録番号
- 200-467-2
- DTXSID米国EPA化学物質番号
- DTXSID3021720
- DTXCID米国EPA化合物番号
- DTXCID101720
- IUPAC
- Ethoxyethane
- 分子式
- C4H10O
- 分子量
- 74.123 g/mol
測定された物性
- 性状
- Diethyl ether appears as a clear colorless liquid with an anesthetic odor. Flash point -49 °F. Less dense than water and slightly soluble in water. Hence floats on water. Vapors are heavier than air. Used as a solvent and to make other chemicals. · Liquid
- 臭い
- Sweetish, pungent odor · Ethereal odor
- 沸点
- 94.3 °F at 760 mmHg (NTP, 1992) · 34.6 °C at 760 mm Hg, 17.9 °C at 400 mm Hg, 2.2 °C at 200 mm Hg
- 融点
- -177.3 °F (NTP, 1992) · -116.3 °C (stable crystals), -123.3 °C (metastable crystals)
- 溶解性
- greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) · Miscible with lower aliphatic alcohols, benzene, chloroform, petroleum ether, fat solvents, many oils, sol in concn hydrochloric acid
- 密度
- 0.714 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7134 at 20 °C/4 °C
- 安定性
- It is slowly oxidized by action of air, moisture, and light, with formation of peroxides. · Peroxide formation may occur in ether containers that have been opened and remain in storage for more than six months. Peroxides may be detonated by friction , impact, or heating.
- 色
- 無色
- 融点・凝固点
- -116 ℃
- 初留点および沸点範囲
- 35 ℃
- 引火点
- -45 ℃
- 燃焼・爆発範囲の上限/下限
- 48 / 1.7 %
- 蒸気圧
- 538 ㎜Hg(25℃)
- 蒸気密度
- 2.6
- 比重
- 0.713
- n-オクタノール/水分配係数(Kow)
- 0.89
- 自然発火温度
- 160 ℃
- 分解温度
- -8.807 ℃(kcal/g)
- 粘度
- 0.2448 cP(20℃)
- 分子量
- 74.12
物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: PubChem · 韓国安全保健公団 SDS
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品9件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Solvent6
- Fuel2
- Propellants, non-motive (blowing agents)1
出典: 米国EPA CompTox
刺激・感作試験の記録
皮膚試験6件・眼試験5件の記録があります。
試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。
試験11件をすべて見る
- Not classified
Skin Irritation · Screening - Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · other guideline: OECD guideline draft proposal for a new guideline, In Vitro Skin Irritation - reliability scoring based on 2009 guideline according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 2002 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) 2008 according to - Category 6.3B (Category 3)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Category 2B
Eye Irritation · Screening - Ambiguous
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants (BCOP Test) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to - Ambiguous
eye irritation: in vitro / ex vivo · Screening · no guideline available other guideline: ICCVAm Test Method Evaluation Report: Appendix G - ICCVAM recommended HET-CAM Method Protocol (Nov. 2006) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
出典: 米国EPA CompTox
関連文献
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- Fibroblast and keratinocyte crosstalk: the effect of a poly(tri[ethylene glycol] ethyl ether methacrylate) thermoresponsive surface on short-term co-culture · 2019
- Screening and analysis of anti-A431 cell proliferative fraction of Euphorbia fischeriana Steud. extract · 2016
- Bioassay Directed Identification of Royal Jelly’s Active Compounds against the Growth of Bacteria Capable of Infecting Cutaneous Wounds · 2013
- Production and application of pantothenyl ethyl ether · 2007
連携データベース 19
- ChEBI
- ChEMBL
- EU CosIng 成分リスト 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto 学術文献検索 2 3 4 5
- UniChem 化学物質統合ID
- Wikidata
- Wikipedia · 韓国語 · 英語 · 日本語 · 中国語
- オーストラリア 化学物質リスト(AICIS)
- 韓国 有害物質GHS情報(環境公団)
- 韓国安全保健公団 SDS
- 韓国食薬処 化粧品原料成分 2
- 大韓化粧品協会 成分辞典
- 中国 既存化粧品原料リスト(IECIC)
- 米国EPA CompTox 2
- 米国EPA 化学物質DB(DSSTox)
- 米国FDA 物質識別番号(UNII)
- 米国FDA 物質登録(GSRS)