Diethyl ether is an ether in which the oxygen atom is linked to two ethyl groups.
定义
Diethyl ether is an ether in which the oxygen atom is linked to two ethyl groups. It has a role as an inhalation anaesthetic, a non-polar solvent and a refrigerant. It is a volatile organic compound and an ether.
来源: PubChem
美国FDA 物质登记 · UNII 0F5N573A2Y · 登记名称 Ether · 单一化学物质
化妆品中的作用
溶解其他成分的基质SOLVENT
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
ETHYL ETHERINCI에틸에터韩国标示名称（食药处标准名）Ethane, 1,1'-oxybis-同义名
- CAS No.化学物质登记号
- 60-29-7
- EC No.欧盟化学品目录编号
- 200-467-2
- DTXSID美国EPA化学品编号
- DTXSID3021720
- DTXCID美国EPA化合物编号
- DTXCID101720
- IUPAC
- Ethoxyethane
- 分子式
- C4H10O
- 分子量
- 74.123 g/mol
实测物性
- 性状
- Diethyl ether appears as a clear colorless liquid with an anesthetic odor. Flash point -49 °F. Less dense than water and slightly soluble in water. Hence floats on water. Vapors are heavier than air. Used as a solvent and to make other chemicals. · Liquid
- 气味
- Sweetish, pungent odor · Ethereal odor
- 沸点
- 94.3 °F at 760 mmHg (NTP, 1992) · 34.6 °C at 760 mm Hg, 17.9 °C at 400 mm Hg, 2.2 °C at 200 mm Hg
- 熔点
- -177.3 °F (NTP, 1992) · -116.3 °C (stable crystals), -123.3 °C (metastable crystals)
- 溶解性
- greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) · Miscible with lower aliphatic alcohols, benzene, chloroform, petroleum ether, fat solvents, many oils, sol in concn hydrochloric acid
- 密度
- 0.714 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7134 at 20 °C/4 °C
- 稳定性
- It is slowly oxidized by action of air, moisture, and light, with formation of peroxides. · Peroxide formation may occur in ether containers that have been opened and remain in storage for more than six months. Peroxides may be detonated by friction , impact, or heating.
- 颜色
- 无色
- 熔点/凝固点
- -116 ℃
- 初沸点和沸程
- 35 ℃
- 闪点
- -45 ℃
- 燃烧或爆炸范围上限/下限
- 48 / 1.7 %
- 蒸气压
- 538 ㎜Hg(25℃)
- 蒸气密度
- 2.6
- 比重
- 0.713
- 正辛醇/水分配系数（Kow）
- 0.89
- 自燃温度
- 160 ℃
- 分解温度
- -8.807 ℃(kcal/g)
- 黏度
- 0.2448 cP(20℃)
- 分子量
- 74.12
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 9 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Solvent6
- Fuel2
- Propellants, non-motive (blowing agents)1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 6 项、眼部试验 5 项。
归类为低4 项
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 11 项试验
- Not classified
Skin Irritation · Screening - Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · other guideline: OECD guideline draft proposal for a new guideline, In Vitro Skin Irritation - reliability scoring based on 2009 guideline according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 2002 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) 2008 according to - Category 6.3B (Category 3)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Category 2B
Eye Irritation · Screening - Ambiguous
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants (BCOP Test) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to - Ambiguous
eye irritation: in vitro / ex vivo · Screening · no guideline available other guideline: ICCVAm Test Method Evaluation Report: Appendix G - ICCVAM recommended HET-CAM Method Protocol (Nov. 2006) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
来源: 美国EPA CompTox
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