2-Ethyl-1,3-hexanediol is an aliphatic alcohol.
How much products actually contain
No product states its amount yet.
Of the products containing it, 56 list it before the 1% line and 86 after it (usually 1% or less).
Products using this ingredient
12 of 141 confirmed · likeliest to carry enough first · See all 141
COSRXCOSRX Hyaluronic Acid Intensive Cream
ILSONatural Mild Clear Nose Pack 5 Sheets
COSRXOne Step Pad (1 of 4 Types) 100 Sheets
COSRXOne Step Original Blemish Pore Clear Pad 100 Sheets /
COSRXCOSRX Hyaluronic Acid Hydra Power Essence
MEDIPEELMEDIPEEL Red Lacto Collagen Eye Patch 1.6g x 60 Sheets
COSRXCOSRX Centella Water Alcohol-Free Toner
COSRXCOSRX Refresh ABC Daily Toner (AHA BHA Vitamin C)
Mary&MayVegan Collagen Fresh Aloe Mask
CIRACLEPore Control Tightening Toner
MoetaMoeta Houttuynia Cordata Perilla Green Tea Shampoo Liquid for Oily Scalp
COSRXAHA/BHA Clarifying Treatment Toner
Definition
2-Ethyl-1,3-hexanediol is an aliphatic alcohol.
Source: PubChem
US FDA substance register · UNII M9JGK7U88V · registered name ETHOHEXADIOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010
Reviewed by CIR: Final Report on the Safety Assessment of Ethyl Hexanediol
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name エチルヘキサンジオール: 本品は、次の化学式で表される脂肪族ジオールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1321-34-2
- CAS No.chemical registry number
- 94-96-2
- EC No.EU chemical inventory number
- 202-377-9
- DTXSIDUS EPA chemical ID
- DTXSID4025292
- DTXCIDUS EPA compound ID
- DTXCID405292
- IUPAC
- 2-Ethylhexane-1,3-diol
- Molecular formula
- C8H18O2
- Molecular weight
- 146.23 g/mol
Measured properties
- Appearance
- Liquid · Colorless, odorless, hygroscopic liquid, [Hawley]
- Odour
- ODORLESS
- Boiling point
- 244.2 °C @ 760 MM HG · 243.1 °C @760 [mm Hg]
- Melting point
- -40 °C
- Solubility
- SOL IN WATER 0.6% WT/WT, SOLUBILITY OF WATER IN ETHOHEXADIOL 10.8% WT/WT, SOL IN ETHANOL, ISOPROPANOL, PROPYLENE GLYCOL, CASTOR OIL · MISCIBLE WITH CHLOROFORM, DIETHYL ETHER
- Density
- 0.9325 @ 22 °C/4 °C · FAINT ODOR OF WITCH HAZEL, DISTILLATION RANGE 241-249 °C, DENSITY: 0.939-0.943 @ 20 °C/20 °C /CRUDE/
- Stability
- STABLE UNDER NORMAL STORAGE CONDITIONS
- Viscosity
- 323 CENTIPOISES @ 20 °C · 323 cP (20degC)
- Melting/freezing point
- -40 ℃
- Initial boiling point and range
- 244.2 ℃
- Flash point
- 127 ℃(open cup)
- Vapour pressure
- 0.01 ㎜Hg (LESS THAN 20degC)
- Water solubility
- 42000 ㎎/ℓ (25degC)
- Vapour density
- 5.03
- Relative density
- 0.9325 (22degC/4degC)
- n-Octanol/water partition coefficient (Kow)
- 1.600
- Auto-ignition temperature
- 360 ℃
- Molecular weight
- 146.22
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified2
- Solvent2
- Fragrance1
- Viscosity modifier1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 4 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Not classified
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Eye Dam. 1
Eye Irritation · Authoritative - Category 2A
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Evaluations of Repellents for Hippelates Eye Gnats · 1967
- Correlation of Cytotoxicity and Antimicrobial Activity of Alkandiols and Their Impact on Stability in Emulsions · 2024
- Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010 · 2011
- Final Report on the Safety Assessment of Ethyl Hexanediol · 1994
- Evaluation of the laboratory mouse model for screening topical mosquito repellents. · 1994
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese