Ingredient Dictionary

ETHYL ISOVALERATE

Ethyl isovalerate is the fatty acid ethyl ester of isovaleric acid.

Definition

Ethyl isovalerate is the fatty acid ethyl ester of isovaleric acid. It has a role as a metabolite. It is a fatty acid ethyl ester and an olefinic compound. It is functionally related to an isovaleric acid.

Source: PubChem

US FDA substance register · UNII 9ZZ5597636 · registered name Ethyl isovalerate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

ETHYL ISOVALERATEINCI에틸아이소발레레이트Korean label name (MFDS standard)Butanoic acid, 3-methyl-, ethyl esterSynonym

CAS No.chemical registry number: 108-64-5
EC No.EU chemical inventory number: 203-602-3
DTXSIDUS EPA chemical ID: DTXSID3047057
DTXCIDUS EPA compound ID: DTXCID1027057

IUPAC: Ethyl 3-methylbutanoate
Molecular formula: C7H14O2
Molecular weight: 130.187 g/mol

Measured properties

Appearance: Ethyl isovalerate appears as a colorless oily liquid with a strong odor similar to apples. Less dense than water. Vapors heavier than air. May mildly irritate skin and eyes. · Liquid
Boiling point: 131.00 to 133.00 °C. @ 760.00 mm Hg · 135 °C
Melting point: -99.3 °C
Solubility: 2 mg/mL at 20 °C · soluble in propylene glycol, 1 ml in 350 ml water, miscible with alcohol, most fixed oils
Density: 0.862-0.866
Colour: colourless
Melting/freezing point: -99 ℃
Initial boiling point and range: 131~135 ℃
Flash point: 50 ℃
Upper/lower flammability or explosive limits: 6.9 / 1.1 %
Vapour pressure: 8.3 ㎜Hg(25℃)
Water solubility: 2000 ㎎/ℓ
Vapour density: 4.49 ()
Relative density: 0.868 (at 20℃)
n-Octanol/water partition coefficient (Kow): 2.26 ((est.))
Molecular weight: 130.19

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance20
Flavouring and nutrient2
No specific technical function1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to