Phenylmethylglycidic ester is an epoxide and a carboxylic acid.
Definition
Phenylmethylglycidic ester is an epoxide and a carboxylic acid.
Source: PubChem
US FDA substance register · UNII UD51D5KR4A · registered name ETHYL METHYLPHENYLGLYCIDATE · mixture
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メチルフェニルグリシッド酸エチル: 本品は、次の化学式で表されるエステルである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 65416-37-7
- CAS No.chemical registry number
- 77-83-8
- EC No.EU chemical inventory number
- 201-061-8
- DTXSIDUS EPA chemical ID
- DTXSID8020591
- DTXCIDUS EPA compound ID
- DTXCID60591
- IUPAC
- Ethyl 3-methyl-3-phenyloxirane-2-carboxylate
- Molecular formula
- C12H14O3
- Molecular weight
- 206.241 g/mol
Measured properties
- Appearance
- liquid
- Initial boiling point and range
- 273.5 ℃
- Flash point
- 134 ℃
- Vapour pressure
- 0.23 ㎩
- Water solubility
- 1 g/ℓ(20℃)
- Vapour density
- 1093 (g/L, 20℃)
- Relative density
- 1.0442 (20℃)
- n-Octanol/water partition coefficient (Kow)
- 3
- Viscosity
- 7.3 ㎟/s
- Molecular weight
- 206.26
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 296 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance289
- Flavouring and nutrient3
- Viscosity modifier2
- Deodorizer2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to other guideline: Magnusson B, Kligman AM (1970) Allergic contact dermatitis in the guinea pig: Identification of contact allergens. CC Thomas, Springfield, IL - Studies Indicate No Significant Irritation
skin corrosion: in vitro / ex vivo · Screening · other guideline: EU Guideline Testing of Chemicals B46 according to other guideline: OECD guideline 429 according to - SkinSens1
Skin Sensitization · QSAR Predicted - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese