Ingredient Dictionary

ETHYL PROPIONATE

Ethyl propionate is a propanoate ester of ethanol.

Definition

Ethyl propionate is a propanoate ester of ethanol. It has a role as a metabolite.

Source: PubChem

US FDA substance register · UNII AT9K8FY49U · registered name ETHYL PROPIONATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

ETHYL PROPIONATEINCIPropanoic acid, ethyl esterSynonym

CAS No.chemical registry number: 105-37-3
EC No.EU chemical inventory number: 203-291-4
DTXSIDUS EPA chemical ID: DTXSID1040110
DTXCIDUS EPA compound ID: DTXCID9020110

IUPAC: Ethyl propanoate
Molecular formula: C5H10O2
Molecular weight: 102.133 g/mol

Measured properties

Appearance: Ethyl propionate appears as a clear colorless liquid with a pineapple-like odor. Flash point 54 °F. Less dense than water and insoluble in water. Vapors are heavier than air. · Colorless liquid with a fruity odor, [Merck Index]
Odour: REMINISCENT OF RUM & PINEAPPLE · Fruity odor
Boiling point: 210 °F at 760 mmHg (USCG, 1999) · 99.2 °C
Melting point: -99 °F (USCG, 1999) · -73.9 °C
Solubility: SOLUBLE IN MOST ORGANIC SOLVENTS · Soluble in alcohol and ether
Density: 0.891 (USCG, 1999) - Less dense than water, will float · 0.8917 @ 20 °C/4 °C
Colour: colourless
Melting/freezing point: -74~-73 ℃
Initial boiling point and range: 99 ℃
Flash point: 12 ℃
Upper/lower flammability or explosive limits: 11 / 1.9 %
Vapour pressure: 40 ㎜Hg (27.2℃)
Vapour density: 3.52
Relative density: 0.886-0.915
n-Octanol/water partition coefficient (Kow): 1.21
Auto-ignition temperature: 440 ℃
Viscosity: 0.49 cP (30 C)
Molecular weight: 102.13

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance13
Flavouring and nutrient3
Solvent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 4 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Category 6.3A (Category 2)
Skin Irritation · Read Across
Classification not possible
Skin Sensitization · Screening
Not classified
Skin Irritation · Screening
Not classified
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Severe Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to other guideline: MatTek Corporation Protocol: Epi Ocular(TM) Eye Irritation Test (OCL-200-EIT) for the prediction of acute ocular irritation of chemicals; for use with MatTek Corporation's Reconsructed Human EpiOcular(TM) Mode; 29 June 2015. according to
Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to