Ethyl propionate is a propanoate ester of ethanol.
定义
Ethyl propionate is a propanoate ester of ethanol. It has a role as a metabolite.
来源: PubChem
美国FDA 物质登记 · UNII AT9K8FY49U · 登记名称 ETHYL PROPIONATE · 单一化学物质
化妆品中的作用
为产品增添香味PERFUMING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
ETHYL PROPIONATEINCIPropanoic acid, ethyl ester同义名
- CAS No.化学物质登记号
- 105-37-3
- EC No.欧盟化学品目录编号
- 203-291-4
- DTXSID美国EPA化学品编号
- DTXSID1040110
- DTXCID美国EPA化合物编号
- DTXCID9020110
- IUPAC
- Ethyl propanoate
- 分子式
- C5H10O2
- 分子量
- 102.133 g/mol
实测物性
- 性状
- Ethyl propionate appears as a clear colorless liquid with a pineapple-like odor. Flash point 54 °F. Less dense than water and insoluble in water. Vapors are heavier than air. · Colorless liquid with a fruity odor, [Merck Index]
- 气味
- REMINISCENT OF RUM & PINEAPPLE · Fruity odor
- 沸点
- 210 °F at 760 mmHg (USCG, 1999) · 99.2 °C
- 熔点
- -99 °F (USCG, 1999) · -73.9 °C
- 溶解性
- SOLUBLE IN MOST ORGANIC SOLVENTS · Soluble in alcohol and ether
- 密度
- 0.891 (USCG, 1999) - Less dense than water, will float · 0.8917 @ 20 °C/4 °C
- 颜色
- 无色
- 熔点/凝固点
- -74~-73 ℃
- 初沸点和沸程
- 99 ℃
- 闪点
- 12 ℃
- 燃烧或爆炸范围上限/下限
- 11 / 1.9 %
- 蒸气压
- 40 ㎜Hg (27.2℃)
- 蒸气密度
- 3.52
- 比重
- 0.886-0.915
- 正辛醇/水分配系数(Kow)
- 1.21
- 自燃温度
- 440 ℃
- 黏度
- 0.49 cP (30 C)
- 分子量
- 102.13
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 17 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Fragrance13
- Flavouring and nutrient3
- Solvent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 3 项、眼部试验 4 项。
归类为低1 项
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 7 项试验
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Not classified
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Severe Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to other guideline: MatTek Corporation Protocol: Epi Ocular(TM) Eye Irritation Test (OCL-200-EIT) for the prediction of acute ocular irritation of chemicals; for use with MatTek Corporation's Reconsructed Human EpiOcular(TM) Mode; 29 June 2015. according to - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) according to
来源: 美国EPA CompTox
相关文献
- Successful Topical Dissolution of Cholesterol Gallbladder Stones Using Ethyl Propionate · 1997
- Ethyl propionate is more effective and less cytotoxic than methyl tert-butyl ether for topical gallstone dissolution. · 1997
- Local and Systemic Effects of Intraduodenal Exposure to Topical Gallstone Solvents Ethyl Propionate and Methyl tert-Butyl Ether in the Rabbit · 1997
- Acute effects of topical methyl tert‐butyl ether or ethyl propionate on gallbladder histology in animals: A comparison of two solvents for contact dissolution of cholesterol gallstones · 1992