Ingredient Dictionary

ETHYL PYRROLIDONE

1-Ethyl-2-pyrrolidinone is a N-alkylpyrrolidine.

Definition

1-Ethyl-2-pyrrolidinone is a N-alkylpyrrolidine.

Source: PubChem

US FDA substance register · UNII H0229SX1CW · registered name ETHYL PYRROLIDONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Ethyl Pyrrolidone is the substituted organic compound that conforms to the formula:

Cosmetic roles

Base that dissolves other ingredientsSOLVENT

Safety & regulatory references

Banned: ASEAN · European Union · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1562

Source: EU prohibited substances (Annex II)

Restriction II/1562

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name エチルピロリドン: 本品は、次の化学式で表される複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

ETHYL PYRROLIDONEINCI에틸피롤리돈Korean label name (MFDS standard)エチルピロリドンJapanese labelling name

CAS No.chemical registry number: 2687-91-4
EC No.EU chemical inventory number: 220-250-6
DTXSIDUS EPA chemical ID: DTXSID3044413
DTXCIDUS EPA compound ID: DTXCID1024413

IUPAC: 1-Ethylpyrrolidin-2-one
Molecular formula: C6H11NO
Molecular weight: 113.16 g/mol

Measured properties

Appearance: Liquid, CBI · Clear colorless to light yellow liquid with an amine odor, [ECHA - Proposal for Harmonised Classification and Labelling] Colorless liquid, [Taminco MSDS]
Initial boiling point and range: 97 ℃(at 20mmHg)
Flash point: 93 ℃
Vapour pressure: 0.103 ㎜Hg (at 25℃)
Water solubility: 115000 ㎎/ℓ (at 25℃)
Vapour density: 3.90
Relative density: 0.9979 (at 20℃)
n-Octanol/water partition coefficient (Kow): -0.04
Viscosity: 0.21 cP
Molecular weight: 113.18

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Solvent4
Processing aids not otherwise specified2
Catalyst2
Chemical reaction regulator2
Intermediate1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 2 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

SkinIrr2
Skin Irritation · QSAR Predicted
SkinSens1
Skin Sensitization · QSAR Predicted
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Classification not possible
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Classification not possible
Eye Irritation · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across