Ethyl salicylate is a hydroxybenzoic acid.
Definition
Ethyl salicylate is a hydroxybenzoic acid.
Source: PubChem
US FDA substance register · UNII 555U6TZ2MV · registered name ETHYL SALICYLATE · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 118-61-6
- EC No.EU chemical inventory number
- 204-265-5
- DTXSIDUS EPA chemical ID
- DTXSID1021958
- DTXCIDUS EPA compound ID
- DTXCID601958
- IUPAC
- Ethyl 2-hydroxybenzoate
- Molecular formula
- C9H10O3
- Molecular weight
- 166.176 g/mol
Measured properties
- Appearance
- Clear colorless to very light yellow liquid with a pleasant odor like wintergreen, [Merck Index] Colorless liquid, [Alfa Aesar MSDS] · Liquid
- Boiling point
- 233.00 to 235.00 °C. @ 760.00 mm Hg · 234 °C
- Melting point
- 1.3 °C
- Solubility
- slightly soluble in water, glycerol, soluble in organic solvents, oils · miscible at room temperature (in ethanol)
- Density
- 1.125-1.131
- Melting/freezing point
- 1 ℃
- Initial boiling point and range
- 232.5 ℃
- Flash point
- 93.8 ℃
- Vapour pressure
- 0.0348 ㎜Hg (25°C)
- Water solubility
- 737 ㎎/ℓ (25℃)
- Vapour density
- 5.7362789092164315
- Relative density
- 1.131
- n-Octanol/water partition coefficient (Kow)
- 2.95
- Molecular weight
- 166.18
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance10
- Flavouring and nutrient2
- Intermediate2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- In vitro human skin absorption of ethyl salicylate, pentyl salicylate, and (Z)-3-hexenyl salicylate from topical formulations: Effects on permeation and distribution. · 2025
- Simultaneous analysis of volatile and semi-volatile components in a topical formulation by gas chromatography using a programmed temperature vaporization inlet and flame ionization detection. · 2019
- The composition of nonbeverage alcohols consumed in Russia in 2015–2017 · 2018
- An improvement of LLNA:DA to assess the skin sensitization potential of chemicals. · 2017
- Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation. · 2012
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese