Definition
US FDA substance register · UNII NBW53A4P49 · registered name ETHYLENE DODECANEDIOATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 54982-83-1
- EC No.EU chemical inventory number
- 259-423-6
- DTXSIDUS EPA chemical ID
- DTXSID1044568
- DTXCIDUS EPA compound ID
- DTXCID9024568
- IUPAC
- 1,4-Dioxacyclohexadecane-5,16-dione
- Molecular formula
- C14H24O4
- Molecular weight
- 256.342 g/mol
Measured properties
- Appearance
- Liquid, CBI · liquid
- Colour
- colourless
- Melting/freezing point
- 16.71~16.73 ℃ (101.32-101.325 kPa)
- Initial boiling point and range
- 337.3 ℃(1 m)
- Flash point
- 166~167 ℃ (101.3 kPa)
- Vapour pressure
- 0.028 ㎩ (25 °C EU Method A.4 GLP)
- Water solubility
- 75 ㎎/ℓ
- Relative density
- 1.05-1.06 (20 deg.C. / 4 dec.C. 20 °C)
- n-Octanol/water partition coefficient (Kow)
- 3.65 (20 °C pH 7.39-7.99 EU Method A.8 GLP)
- Auto-ignition temperature
- 385 ℃ (&, gt, = 1003.4 &, lt, = 1005 hPa EU Method A.15 GLP)
- Viscosity
- 96.934-96.935 cP (dynamic20 °C OECD Test Guideline 114)
- Molecular weight
- 256.34
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 21 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance17
- Deodorizer4
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Source: US EPA CompTox dashboard
Related literature
- RIFM fragrance ingredient safety assessment, ethylene brassylate, CAS Registry Number 105-95-3. · 2016 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Fragrance material review on ethylene dodecanedioate. · 2011 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- PubMed 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata