Ethylenediamine is an alkane-alpha,-diamine in which the alkane is ethane.
Definition
Ethylenediamine is an alkane-alpha,-diamine in which the alkane is ethane. It has a role as a GABA agonist. It derives from a hydride of an ethane.
Source: PubChem
US FDA substance register · UNII 60V9STC53F · registered name Ethylenediamine · single chemical substance
Ethylenediamine is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- Canada
Source: Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Danger · H412 (category 3) · H317 (category 1) · H334 (category 1) · +5 more
Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 107-15-3
- EC No.EU chemical inventory number
- 203-468-6
- DTXSIDUS EPA chemical ID
- DTXSID5021881
- DTXCIDUS EPA compound ID
- DTXCID501881
- IUPAC
- Ethane-1,2-diamine
- Molecular formula
- C2H8N2
- Molecular weight
- 60.1 g/mol
Measured properties
- Appearance
- Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor. Flash point of 91 °F and a melting point of 47 °F. Corrosive to tissue. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Density 7.5 lb / gal. Used to make other chemicals and as a fungicide. · CBI, Liquid, Other Solid
- Odour
- Ammonia-like
- Boiling point
- 241 °F at 760 mmHg (EPA, 1998) · 116-117 °C
- Melting point
- 46 °F (EPA, 1998) · 8.5 °C
- Solubility
- greater than or equal to 100 mg/mL at 63 °F (NTP, 1992) · Crystals, sublimes without melting, freely sol in water, practically insol in alc /Dihydrochloride/
- Density
- 0.898 at 77 °F (EPA, 1998) - Less dense than water, will float · 0.898 @ 25 °C/4 °C
- Odour threshold
- 16000 (mg/l )
- pH
- 11.9
- Melting/freezing point
- 8.5 ℃
- Initial boiling point and range
- 116~117 ℃
- Flash point
- 34 ℃(c.c.)
- Evaporation rate
- 0.91
- Flammability (solid, gas)
- flammable
- Upper/lower flammability or explosive limits
- 16.6 / 2.5 %
- Vapour pressure
- 12.1 ㎜Hg (25℃)
- Water solubility
- 1X10+6 ㎎/ℓ
- Vapour density
- 2.07
- Relative density
- 0.898
- n-Octanol/water partition coefficient (Kow)
- -2.04 (pH 13)
- Auto-ignition temperature
- 385 ℃
- Decomposition temperature
- -452.6 ( cal/g mol )
- Viscosity
- 0.0154 (25℃)
- Molecular weight
- 60.1
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 19 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified3
- Chemical reaction regulator3
- Chelating agent2
- Monomers2
- Intermediate2
- Soil amendments1
- Lubricating agent1
- Hardener1
4 other uses
- Elasticizer1
- Tracer1
- No specific technical function1
- Corrosion inhibitor1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
11 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 14 studies
- Category 1
Skin Sensitization · Screening - Category 8.2B (Category 1B)
Skin Irritation · Read Across - Category 1
Skin Irritation · Screening - Sah
Skin Sensitization · Authoritative - Skin Sens. 1
Skin Sensitization · Screening - Skin corrosion/irritation - Category 1B
Skin Irritation · Screening - Skin Corr. 1B
Skin Irritation · Screening - Skin Corr. 1B
Skin Irritation · Authoritative - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Skin Sens. 1
Skin Sensitization · Authoritative - Skin sensitization - Category 1
Skin Sensitization · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Eye Dam. 1
Eye Irritation · Screening - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Ethylenediamine-Induced Asthma1,2 · 2015
- Ethylenediamine: a possible cause of airborne urticaria and indoor air complaints · 1998
- Ethylenediamine contact dermatitis · 1984
- Why patients allergic to ethylenediamine do not react to topical steroids containing ethylenediamine. · 1984
- Ethylenediamine-induced asthma. · 1980
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese