Definition
US FDA substance register · UNII HR49R9S6XG · registered name ETHYLHEXYL ACRYLATE · single chemical substance
Ethylhexyl Acrylate is the organic compound that conforms to the formula:
Cosmetic roles
Holds powders togetherBINDING
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アクリル酸エチルヘキシル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
ETHYLHEXYL ACRYLATEINCI에틸헥실아크릴레이트Korean label name (MFDS standard)2-Propenoic acid, 2-ethylhexyl esterSynonymアクリル酸エチルヘキシルJapanese labelling name
- CAS No.chemical registry number
- 103-11-7
- EC No.EU chemical inventory number
- 203-080-7
- DTXSIDUS EPA chemical ID
- DTXSID9025297
- DTXCIDUS EPA compound ID
- DTXCID405297
- IUPAC
- 2-Ethylhexyl prop-2-enoate
- Molecular formula
- C11H20O2
- Molecular weight
- 184.279 g/mol
Measured properties
- Appearance
- liquid
- Colour
- colourless
- Odour threshold
- (0.02 mg/l)
- Melting/freezing point
- -90 ℃
- Initial boiling point and range
- 213.5 ℃
- Flash point
- 86 ℃(c.c.)
- Flammability (solid, gas)
- combustible
- Upper/lower flammability or explosive limits
- 6.4 / 0.8 %
- Vapour pressure
- 0.178 ㎜Hg (@ 25 ℃)
- Water solubility
- 100 ㎎/ℓ (@ 25 ℃)
- Vapour density
- 6.35
- Relative density
- 0.89
- n-Octanol/water partition coefficient (Kow)
- 3.67
- Auto-ignition temperature
- 252 ℃
- Viscosity
- 1.75 cP (@ 20 ℃)
- Molecular weight
- 184.28
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 20 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Binder5
- Intermediate3
- Monomers3
- Anti-stain agent2
- Surfactant (surface active agent)2
- Processing aids not otherwise specified2
- Adhesion/cohesion promoter1
- Defoamer1
1 other uses
- Cleaning agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
13 skin studies and 4 eye studies are on record.
Classed as moderate2
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 17 studies
- Category 1
Skin Sensitization · Screening - Category 2
Skin Irritation · Screening - Skin Irrit. 2
Skin Irritation · Authoritative - Skin sensitization - Category 1
Skin Sensitization · Screening - Sh
Skin Sensitization · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Skin irritation - category 2
Skin Irritation · Screening - Skin sensitisation - category 1
Skin Sensitization · Screening - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Skin Sens. 1
Skin Sensitization · Authoritative - Ambiguous
skin corrosion: in vitro / ex vivo · Screening · other guideline: Commission directive 2000/33/EC, methods for the determination of toxicity, publication No. L 136, B. 40: Skin corrosion, adopted 08 June 2000 and OECD Guideline, draft proposal for a new guideline: "In vitro Skin Corrosion tests" according to - Skin corrosion/irritation - Category 2
Skin Irritation · Screening - Category 2
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Hazardous Substances Labelling Act Regulations, Section 191.12, published in the Federal Register -29 F.R. 13009, 1964. equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- Critical evaluation of 2-ethylhexyl acrylate dermal carcinogenicity studies using contemporary criteria. · 2018
- Water-compatible cross-linked pyrrolidone acrylate pressure-sensitive adhesives with persistent adhesion for transdermal delivery: Synergistic effect of hydrogen bonding and electrostatic force. · 2024
- Murine Skin Carcinogenesis and the Role of Immune System Dysregulation in the Tumorigenicity of 2-Ethylhexyl Acrylate · 2020
- A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. · 2018
- FORMULATION AND EVALUATION OF RAMIPRIL TRANSDERMAL PATCH · 2014
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese