Etidronic acid is a 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position.
How much products actually contain
No product states its amount yet.
Of the products containing it, 7 list it before the 1% line and 13 after it (usually 1% or less).
Products using this ingredient
12 of 20 confirmed · likeliest to carry enough first · See all 20
IGK HairIGK Hair Paid In Full High Gloss Intense Repair Treatment
Ato&O2Low-Temperature Aged Baby Ampoule Soap
SEVENPMReal Comb Magic Perm
AYUNCHEPro Down Cream
amikaamika bust your brass | cool blonde strength repair conditioner
amikaamika the kure | strength repair conditioner
PARKJUN BEAUTY LABPPT Protein Treatment 250
OribeOribe Desertland Soap
OribeOribe Valley of Flowers Soap
MOREMO KeratinRoot Touch-Up Magic Straight
OLAPLEXOLAPLEX No.6 Bond Smoother®
TOOQEasy & Gentle Bleach
Definition
Etidronic Acid is the organic diphosphonic acid that conforms to the formula
US FDA substance register · UNII M2F465ROXU · registered name Etidronic Acid · single chemical substance
Etidronic acid is a 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces. It has a role as an antineoplastic agent, a chelator and a bone density conservation agent. It is a conjugate acid of an etidronic acid(2-).
Source: PubChem
Cosmetic roles
Safety & regulatory references
- Restricted
- China · South Korea · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Argentina · Brazil
- Field of application and/or use : (a) Products for hair care (b) Soaps
- Maximum concentration permitted at final product : a.- 1.5% (calculated as Etidronic Acid) b.- 0.2% (calculated as Etidronic Acid)
ASEAN
- Field of application and/or use : (a) Hair-care (b) Soap
- Maximum authorised concentration in the finished cosmetic product : (a) 1.5% expressed as etidronic acid (b) 0.2% expressed as etidronic acid
European Union
- Product Type, body parts : (a) Hair product (b) Soap
- Maximum concentration in ready for use preparation : (a) 1.5% (as etidronic acid) (b) 0.2% (as etidronic acid)
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
EU Cosmetics Regulation, Annex III (restricted substances), entry 53 · maximum concentration (a) 1.5% (as etidronic acid) (b) 0.2% (as etidronic acid) · applies to (a) Hair product (b) Soap
Restriction III/53
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report: Safety Assessment of Etidronic Acid and Its Salts as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name エチドロン酸: 本品は、次の化学式で表される有機ジホスホン酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 2809-21-4
- EC No.EU chemical inventory number
- 220-552-8
- DTXSIDUS EPA chemical ID
- DTXSID6023028
- DTXCIDUS EPA compound ID
- DTXCID103028
- IUPAC
- (1-Hydroxyethane-1,1-diyl)bis(phosphonic acid)
- Molecular formula
- C2H8O7P2
- Molecular weight
- 206.027 g/mol
Measured properties
- Appearance
- CBI, Dry Powder, Liquid · White odorless powder, [MSDSonline]
- Boiling point
- 578.8
- Melting point
- 198-199 · 105 °C
- Solubility
- 1.15e+01 g/L
- Vapour pressure
- 0.000000000124 ㎜Hg (at 25℃ (est.))
- n-Octanol/water partition coefficient (Kow)
- -3.49
- Decomposition temperature
- (&, gt, 200 ℃)
- Molecular weight
- 206.02
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 51 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chelating agent28
- Corrosion inhibitor5
- Processing aids not otherwise specified4
- Stabilizing agent3
- Lubricating agent2
- Anti-scaling agent2
- Oxidizing agent1
- Dispersing agent1
5 other uses
- Fragrance1
- Intermediate1
- Anti-stain agent1
- Cleaning agent1
- Dye1
Source: US EPA CompTox dashboard
Related literature
Linked databases 25
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU restricted substances (Annex III)
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- PubChem 2
- Tlooto literature search 2
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese