ETIDRONIC ACID

Etidronic Acid is the organic diphosphonic acid that conforms to the formula

美国FDA 物质登记 · UNII M2F465ROXU · 登记名称 Etidronic Acid · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Etidronic acid is a 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces. It has a role as an antineoplastic agent, a chelator and a bone density conservation agent. It is a conjugate acid of an etidronic acid(2-).

来源: PubChem

限用

韩国 · 英国 · 中国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 英国化妆品法规

阿根廷 · 巴西

• Field of application and/or use : (a) Products for hair care (b) Soaps
• Maximum concentration permitted at final product : a.- 1.5% (calculated as Etidronic Acid) b.- 0.2% (calculated as Etidronic Acid)

东盟

• Field of application and/or use : (a) Hair-care (b) Soap
• Maximum authorised concentration in the finished cosmetic product : (a) 1.5% expressed as etidronic acid (b) 0.2% expressed as etidronic acid

欧盟

• Product Type, body parts : (a) Hair product (b) Soap
• Maximum concentration in ready for use preparation : (a) 1.5% (as etidronic acid) (b) 0.2% (as etidronic acid)

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

欧盟化妆品法规 附录III（限用物质） 第53项 · 最高浓度 (a) 1.5% (as etidronic acid) (b) 0.2% (as etidronic acid) · 适用 (a) Hair product (b) Soap

来源: 欧盟限用成分（附录III）

Restriction III/53

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Final Report: Safety Assessment of Etidronic Acid and Its Salts as Used in Cosmetics

来源: 美国CIR 安全性评估