Ficin is an organoiodine compound.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1 list it before the 1% line and 3 after it (usually 1% or less).
Products using this ingredient
4 of 4 confirmed · likeliest to carry enough first
Definition
Ficin is an organoiodine compound.
Source: PubChem
Ficus proteinase. Proteolytic enzyme isolated from the latex of the Fig, Ficus carica L., Moraceae
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name フィシン: 本品は、イチジク Ficus carica の乳汁から単離されるタンパク分解酵素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 9001-33-6
- EC No.EU chemical inventory number
- 232-599-1
- DTXSIDUS EPA chemical ID
- DTXSID3093787
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chemical reaction regulator2
- Softener and conditioner1
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Skin Irrit. 2
Skin Irritation · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative
Source: US EPA CompTox dashboard
Related literature
- Novel fluorescent ficin-templated Ni nanoclusters for nucleus imaging: a green and biocompatible alternative to traditional DNA stain. · 2025
- Proteolytic Enzyme Activities of Bromelain, Ficin, and Papain from Fruit By-Products and Potential Applications in Sustainable and Functional Cosmetics for Skincare · 2025
- Efficacy of ficin and peroxyacetic acid against Salmonella enterica serovar Thompson biofilm on plastic, eggshell, and chicken skin. · 2022
- Proteases and itch – a human and animal model of non‐histaminergic itch using cysteine protease Ficin · 2022
- Anti-biofilm and wound-healing activity of chitosan-immobilized Ficin. · 2020