Fisetin is a 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1 list it before the 1% line and 0 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
Fisetin is a 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'. It has a role as a geroprotector, an antioxidant, a metabolite, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-inflammatory agent and a plant metabolite. It is a 3'-hydroxyflavonoid, a tetrahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a fisetin(1-).
Source: PubChem
US FDA substance register · UNII OO2ABO9578 · registered name FISETIN · single chemical substance
Fisetin is the organic compound
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name フィセチン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 528-48-3
- EC No.EU chemical inventory number
- 208-434-4
- DTXSIDUS EPA chemical ID
- DTXSID4022317
- DTXCIDUS EPA compound ID
- DTXCID902317
- IUPAC
- 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
- Molecular formula
- C15H10O6
- Molecular weight
- 286.239 g/mol
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Dye1
Source: US EPA CompTox dashboard
Related literature
- Exploring the Pharmacological Potential of Fisetin: A Comprehensive Review · 2024
- Recent advancement of fisetin-based nanoformulations in the management of psoriasis · 2025
- Preclinical Evaluation of Fisetin in the Management of Diabetic Foot Ulcer in Wistar Rats. · 2025
- Fisetin alleviates chronic urticaria by inhibiting mast cell activation via MRGPRX2. · 2023
- Fisetin induces apoptosis in human skin cancer cells through downregulating MTH1 · 2022
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese