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成分词典

成分词典

FORMALDEHYDE

Formaldehyde (gas) can cause cancer according to an independent committee of scientific and health experts.

分子结构

定义

Formaldehyde (gas) can cause cancer according to an independent committee of scientific and health experts.

来源: PubChem

美国FDA 物质登记 · UNII 1HG84L3525 · 登记名称 Formaldehyde · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

Formaldehyde is the aldehyde that conforms to the formula:

化妆品中的作用

抑制微生物生长ANTIMICROBIAL防止产品中微生物滋生PRESERVATIVE使酒精不可饮用DENATURANT

安全与法规参考

禁用
韩国 · 欧盟 · 台湾 · 英国
限用·禁用
韩国 · 欧盟 · 日本 · 台湾

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 台湾FDA 化妆品成分 · 英国化妆品法规

东盟

  • Field of application and/or use : Nail hardeners
  • Maximum authorised concentration in the finished cosmetic product : 2.2% calculated as formaldehyde
  • Other limitations and requirements : As a preservative, see Annex VI, Part1, No. 5. Allowed only in Lao PDR and Vietnam
  • Conditions of use and warning which must be printed on the labels : Protect cuticles with grease or oil. Contains formaldehyde (2)

加拿大

  • Conditions of Use by product type : (a) Not permitted in aerosol products. (b) Non-aerosol products that release formaldehyde vapours when used according to directions. (c) Oral products (d) Non-oral products as a preservative (e) Nail hardeners, must be sold with nail shields and directions for use.
  • Maximum Concentration Permitted : (b) 0.01% (c) 0.1% (d) 0.2% (e) 5.0%
  • Warnings and Cautionary Statements: (to the effect of) : e) "This product contains formaldehyde which has the potential to cause skin sensitivity."

中国

  • 最大配合量 : 5%

来源: 韩国食药处 化妆品法规信息

韩国有毒物质 GHS 分类: 危险 · H311 (第3类) · H314 (第1类) · H330 (第2类) · 另有 6 项

来源: 韩国有毒物质 GHS 信息(环境公团)

欧盟化妆品法规 附录II(禁用物质) 第1577项

来源: 欧盟禁用成分(附录II)

Restriction II/1577 · Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2004/2005

来源: 美国CIR 安全性评估

Reviewed by CIR: Amended Safety Assessment of Formaldehyde and Methylene Glycol as Used in Cosmetics

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report on the Safety Assessment of Formaldehyde

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

FORMALDEHYDEINCI포름알데하이드韩国标示名称(食药处标准名)
CAS No.化学物质登记号
50-00-0
EC No.欧盟化学品目录编号
200-001-8
DTXSID美国EPA化学品编号
DTXSID7020637
DTXCID美国EPA化合物编号
DTXCID30637
IUPAC
Formaldehyde
分子式
CH2O
分子量
30.026 g/mol

实测物性

颜色
无色
嗅觉阈值
0.5~1.0 ppm
pH
2.8~4
熔点/凝固点
-92 ℃
初沸点和沸程
-19~-21 ℃ (1013.25 hPa)
闪点
85 ℃(, 50℃)
燃烧或爆炸范围上限/下限
73 / 7 %
蒸气压
1.3187 hPa(20℃)
溶解度
400 g/ℓ(20℃)
比重
1.15
正辛醇/水分配系数(Kow)
0.35 (log Pow, 25℃)
自燃温度
430 ℃(1013.25 hPa)
黏度
2.45 cP(25℃)
分子量
30.0258

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 134 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Degradant/impurity (EPA)28
  • Monomers25
  • No specific technical function14
  • Preservative13
  • Binder12
  • Biocide8
  • Processing aids not otherwise specified8
  • Soil amendments5
其余用途 15 项
  • Adhesion/cohesion promoter5
  • Intermediate2
  • Sealant (barrier)2
  • Embalming agent1
  • Elasticizer1
  • Chemical reaction regulator1
  • Fixing agent (mordant)1
  • Insulators1
  • Deodorizer1
  • Chelating agent1
  • Plasticizer1
  • Surfactant (surface active agent)1
  • Energy releasers (explosives, motive propellant)1
  • Propellants, non-motive (blowing agents)1
  • Dispersing agent1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 15 项、眼部试验 4 项。

归类为刺激性高1 项归类为中等1 项

各项试验结论不一(最多的结论占 50%),因此不能断定该成分有刺激性。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 19 项试验
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
  • Category 8.2C (Category 1C)
    Skin Irritation · Read Across
  • Sh
    Skin Sensitization · Authoritative
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • Skin Sens. 1
    Skin Sensitization · Screening
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Ambiguous
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Skin Sens. 1
    Skin Sensitization · Authoritative
  • Skin Corr. 1B
    Skin Irritation · Authoritative
  • Skin Corr. 1B
    Skin Irritation · Screening
  • Corrosive
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Skin sensitisation - category 1
    Skin Sensitization · Screening
  • Skin corrosion - category 1
    Skin Irritation · Screening
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Serious eye damage/eye irritation - Category 2
    Eye Irritation · Screening
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Eye Dam. 1
    Eye Irritation · Screening

来源: 美国EPA CompTox

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