What is this ingredient?

미국 FDA 물질 등록 · UNII DJ1HGI319P · 등록명 Furfural · 단일 화학물질

All ingredients

Ingredient Dictionary

FURFURAL

Furfural is an aldehyde that is furan with the hydrogen at position 2 substituted by a formyl group.

Definition

US FDA substance register · UNII DJ1HGI319P · registered name Furfural · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Furfural is the cyclic aldehyde that conforms to the formula:

Furfural is an aldehyde that is furan with the hydrogen at position 2 substituted by a formyl group. It has a role as a metabolite and a Maillard reaction product. It is an aldehyde and a member of furans. It is functionally related to a furan.

Source: PubChem

Cosmetic roles

Base that dissolves other ingredientsSOLVENTListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Restricted: International fragrance standard (IFRA) · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · IFRA fragrance standards · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

ASEAN

Maximum authorised concentration in the finished cosmetic product : 0.001%

European Union

Maximum concentration in ready for use preparation : 0,001 %

Source: MFDS (Korea) cosmetic regulatory information

Korea’s toxic-substance GHS classification: Danger · H330 (category 2) · H335 (category 3) · H351 (category 2) · +3 more

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 312 · maximum concentration 0,001 %

Source: EU restricted substances (Annex III)

Restriction III/312 · SCCS opinion: Furfural; Opinion on Furfural

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name フルフラール: 本品は、次の化学式で表される環状アルデヒドである。

Source: JCIA labelling names (Japan)

Names & identifiers

FURFURALINCI퍼퓨랄Korean label name (MFDS standard)2-FurancarboxaldehydeSynonymフルフラールJapanese labelling name

CAS No.chemical registry number: 98-01-1
EC No.EU chemical inventory number: 202-627-7
DTXSIDUS EPA chemical ID: DTXSID1020647
DTXCIDUS EPA compound ID: DTXCID50647

IUPAC: Furan-2-carbaldehyde
Molecular formula: C5H4O2
Molecular weight: 96.085 g/mol

Measured properties

Appearance: Furfural appears as colorless or reddish-brown mobile liquids with a penetrating odor. Flash points 140 °F. Denser than water and soluble in water. Vapors heavier than air. May be toxic by ingestion, skin absorption or inhalation. · Liquid
Odour: Peculiar odor, somewhat resembling the odor of benzaldehyde · ... Almond-like odor ...
Boiling point: 323.1 °F at 760 mmHg (NTP, 1992) · 161.7 °C
Melting point: -33.7 °F (NTP, 1992) · -38.1 °C
Solubility: 50 to 100 mg/mL at 64 °F (NTP, 1992) · Soluble in alcohol, ether, 8.3% soluble in water at 20 °C
Density: 1.159 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.1594 g/cu cm at 20 °C
Odour threshold: 0.2 ppm
Melting/freezing point: -38.1 ℃
Initial boiling point and range: 161.7 ℃
Flash point: 60 ℃(C.C.)
Evaporation rate: &amp, lt, 1
Upper/lower flammability or explosive limits: 19.3 / 2.1 %
Vapour pressure: 2.21 ㎜Hg (25℃)
Water solubility: 7.41X10+4 ㎎/ℓ (25℃)
Vapour density: 3.31
Relative density: 1.16
n-Octanol/water partition coefficient (Kow): 0.41
Auto-ignition temperature: 315 ℃
Decomposition temperature: 560 (kcal/mol)
Viscosity: 1.587 (25℃, mPa-s)
Molecular weight: 96.1

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 20 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance7
No specific technical function7
Flavouring and nutrient2
Intermediate1
Solvent1
Hardener1
Monomers1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 6 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 14 studies

Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EPA OPPTS 870.2600 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Skin Irrit. 2
Skin Irritation · Authoritative
Category 2
Skin Irritation · Screening
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to
Skin corrosion/irritation - Category 2
Skin Irritation · Screening
Skin irritation - category 2
Skin Irritation · Screening
Category 2A
Eye Irritation · Screening
Eye Irrit. 2
Eye Irritation · Authoritative
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Eye irritation - category 2A
Eye Irritation · Screening
Serious eye damage/eye irritation - Category 2A
Eye Irritation · Screening