2-furoic acid is a furoic acid having the carboxylic acid group located at position 2.
Definition
2-furoic acid is a furoic acid having the carboxylic acid group located at position 2. It has a role as an inhibitor, a Saccharomyces cerevisiae metabolite, a plant metabolite, a human xenobiotic metabolite and a bacterial xenobiotic metabolite. It is a conjugate acid of a 2-furoate.
Source: PubChem
US FDA substance register · UNII P577F6494A · registered name 2-Furoic acid · single chemical substance
Furoic Acid is the organic compound that conforms to the formula:
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 88-14-2
- EC No.EU chemical inventory number
- 201-803-0
- DTXSIDUS EPA chemical ID
- DTXSID6041420
- DTXCIDUS EPA compound ID
- DTXCID4021420
- IUPAC
- Furan-2-carboxylic acid
- Molecular formula
- C5H4O3
- Molecular weight
- 112.084 g/mol
Measured properties
- Appearance
- Liquid · Solid
- Boiling point
- 230.00 to 232.00 °C. @ 760.00 mm Hg
- Melting point
- 133.5 °C
- Solubility
- 37.1 mg/mL at 15 °C
- Melting/freezing point
- 129~133 ℃
- Initial boiling point and range
- 232.14 ℃(760 mmHg)
- Flash point
- 94.195 ℃
- Vapour pressure
- 0.033 ㎜Hg (25°C)
- Water solubility
- 36 g/㎖ (20℃)
- Vapour density
- 3.8688298239558163
- n-Octanol/water partition coefficient (Kow)
- 1
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient2
- Intermediate1
- Cleaning agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- A hydrogel dressing derived from furoic acid/betaine co-modified chitosan: accelerating Staphylococcus aureus -infected wound healing. · 2026
- Novel different furoic acid‐linked axial silicon phthalocyanines: Design, syntheses, cholinesterases tyrosinase inhibitory, and DNA damage studies · 2023
- Fluticasone furoate/fluticasone propionate – different drugs with different properties · 2011
- Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells. · 2007
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese