Fusel oil a combination of amyl Alcohols, primarily isoamyl Alcohol and 2-methyl-1-butanol.
Definition
US FDA substance register · UNII 2NK7O363Q6 · registered name FUSEL OIL · mixture
Fusel oil a combination of amyl Alcohols, primarily isoamyl Alcohol and 2-methyl-1-butanol. Other Alcohols, acids, esters and aldehydes may also be present
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 8013-75-0
- EC No.EU chemical inventory number
- 232-395-2
- DTXSIDUS EPA chemical ID
- DTXSID6027688
Measured properties
- Appearance
- liquid
- Melting/freezing point
- &, lt, -20 ℃ (1013 hPa)
- Initial boiling point and range
- 60~143 ℃ (1013 hPa)
- Flash point
- 12 ℃(101 325 Pa)
- Vapour pressure
- &, lt, 78.7 ㎪ (20-25°C)
- Water solubility
- 41580 ㎎/ℓ
- Vapour density
- 3.04280289955126
- Relative density
- 0.75 - 0.9 (20 °C)
- n-Octanol/water partition coefficient (Kow)
- -1.26~-0.14
- Auto-ignition temperature
- 300 ℃ (101 325 Pa)
- Viscosity
- &, gt, 3.64 to &, lt, 3.88 (20°C)
- Molecular weight
- 88.15
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance3
- Solvent2
- Fuel2
- Flavouring and nutrient1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Moderate or Mild Irritation
skin irritation: in vivo · Screening · EPA OTS 798.4470 (Acute Dermal Irritation) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · EPA OTS 798.4500 (Acute Eye Irritation) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 38, No 187, s 1500.41, S. 27019 (1973) according to
Source: US EPA CompTox dashboard
Related literature
- Hybrid Process Flow Diagram for Separation of Fusel Oil into Valuable Components · 2024
- Fusel Oil: Chemical Composition and an Overview of Its Potential Application · 2023
- Enzymatic synthesis optimization of isoamyl butyrate from fusel oil · 2021
- Development of Technology for Producing a Fat Composition Based on Ester for Fattening Leather · 2019
- Application of an immobilized Rhizopus oryzae lipase to batch and continuous ester synthesis with a mixture of a lauric acid and fusel oil · 2018
Linked databases 10
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- KOSHA safety data sheets (Korea)
- Tlooto literature search 2 3 4 5
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese