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Ingredients

Ingredient Dictionary

GENISTEIN

Genistein is a 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 1 list it before the 1% line and 0 after it (usually 1% or less).

Products using this ingredient

1 of 1 confirmed · likeliest to carry enough first

Definition

Genistein is a 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties. It has a role as a geroprotector, an antineoplastic agent, a tyrosine kinase inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a plant metabolite, a phytoestrogen and a human urinary metabolite. It is a conjugate acid of a genistein(1-).

Source: PubChem

US FDA substance register · UNII DH2M523P0H · registered name GENISTEIN · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Genistein is the organic compound that conforms to the formula:

Cosmetic roles

Skin conditioning not covered aboveSKIN CONDITIONING - MISCELLANEOUS

Safety & regulatory references

European Union

  • Maximum concentration in ready for use preparation : 0.007 %

Source: MFDS (Korea) cosmetic regulatory information

EU Cosmetics Regulation, Annex III (restricted substances), entry 373 · maximum concentration 0,007 %

Source: EU restricted substances (Annex III)

Restriction III/373

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ゲニステイン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

GENISTEININCI제니스테인Korean label name (MFDS standard)ゲニステインJapanese labelling name
CAS No.chemical registry number
446-72-0
EC No.EU chemical inventory number
207-174-9
DTXSIDUS EPA chemical ID
DTXSID5022308
DTXCIDUS EPA compound ID
DTXCID002308
IUPAC
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Molecular formula
C15H10O5
Molecular weight
270.24 g/mol

Measured properties

Appearance
Solid · Rectangular or six-sided rods from 60% alcohol. Dendritic needles from ether
Melting point
301.5 dec °C · 297-298 °C (slight decomposition)
Solubility
Soluble in the usual organic solvents, soluble in dilute alkalies with yellow color. Practically insoluble in water.
Odour
odourless
pH
7.08
Melting/freezing point
301.5 ℃
Initial boiling point and range
464.36 ℃
Vapour pressure
0.00000000000512 ㎜Hg
Water solubility
258 ㎎/ℓ
n-Octanol/water partition coefficient (Kow)
2.84
Molecular weight
270.24

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Softener and conditioner1

Source: US EPA CompTox dashboard

Related literature

Linked databases 20