Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var.
Definition
US FDA substance register · UNII WB232T95AV · registered name GINSENOSIDE RD · single chemical substance
Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as an anti-inflammatory drug, an immunosuppressive agent, a neuroprotective agent, an apoptosis inducer, a vulnerary and a plant metabolite. It is a beta-D-glucoside, a tetracyclic triterpenoid and a ginsenoside. It is functionally related to a (20S)-ginsenoside Rg3.
Source: PubChem
Ginsenoside Rd is the saponin isolated from Acanthopanax senticosus that conforms to the formula
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 52705-93-8
- EC No.EU chemical inventory number
- 258-118-5
- DTXSIDUS EPA chemical ID
- DTXSID301031221
- DTXCIDUS EPA compound ID
- DTXCID701516233
- IUPAC
- 20-(beta-D-Glucopyranosyloxy)-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
- Molecular formula
- C48H82O18
- Molecular weight
- 947.166 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Antioxidant1
Source: US EPA CompTox dashboard
Related literature
- Skin-healing properties of ginsenoside Rd against Ultraviolet-B-induced photooxidative stress through up-regulation of antioxidant components in HaCaT keratinocytes · 2021
- Skin Wrinkle Improvement Effect of Ginseng Above-ground Part and Ginsenoside Content by Harvesting Period · 2024
- Ginsenoside Rd Inhibits the Metastasis of Colorectal Cancer via Epidermal Growth Factor Receptor Signaling Axis · 2019
- 1327 Effect of ginsenoside Rd on dermal epidermal junction in fibroblast · 2018
- Anti-wrinkle Effect of Rare Ginsenosides, Produced from Ginsenoside Rd · 2015
Linked databases 14
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata