GLUCONOLACTONE

C

无对照或复方产品研究

D-glucono-1,5-lactone is an aldono-1,5-lactone obtained from D-gluconic acid. It has a role as an animal metabolite and a mouse metabolite. It is a gluconolactone and an aldono-1,5-lactone. It is functionally related to a D-gluconic acid.

来源: PubChem

美国FDA 物质登记 · UNII WQ29KQ9POT · 登记名称 Gluconolactone · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

D-Glucono-1,5-lactone

加拿大

• Conditions of Use by product type : (a) Products for use on the skin for consumer use. Manufacturer or importer to provide pH levels. (b) Products for use on the skin for professional use: Manufacturer must provide Health Canada with evidence of safety including: 1. pH levels 2. AHA concentrations 3. Directions for use 4. Clinical studies demonstrating minimal skin irritation (c) Products intended to be diluted in bath water may contain levels of AHAs exceeding 10% (d) Other cosmetics (e) Any cosmetics
• Maximum Concentration Permitted : (a) Between 3% and 18% total mono-AHA equivalents with a pH equal to or greater than 3.5 (b) Between 18% and 30% total mono-AHA equivalents and/or a pH between 3.0 to 3.5 (d) Between 3% and 30% total mono-AHA equivalents with a pH equal to or greater than 3.0 (e) 3%
• Warnings and Cautionary Statements: (to the effect of) : (a) and (b) : "Use only as directed", "Avoid contact with the eyes", "If irritation persists, discontinue use and consult a physician", "It is recommended that prior to exposure to the sun, users cover areas where AHAs have been applied with sunscreen" Product labels should contain appropriate directions regarding frequency and/or duration of use. (b only) "For professional use only" (d) "Use only as directed", "Avoid contact with eyes", "Discontinue use if rash or irritation occurs"

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

Other restriction: ban substances that deplete the ozone layer

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Safety Assessment of Glycolactones as Used in Cosmetics

来源: 美国CIR 安全性评估