D-glucurono-6,3-lactone is a glucuronolactone.
Definition
D-glucurono-6,3-lactone is a glucuronolactone. It has a role as a mouse metabolite and a human metabolite. It is functionally related to a D-glucuronic acid.
Source: PubChem
US FDA substance register · UNII XE4Y3016M9 · registered name GLUCUROLACTONE · single chemical substance
D-Glucuronic acid, .gamma.-lactone
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 32449-92-6
- EC No.EU chemical inventory number
- 251-053-3
- DTXSIDUS EPA chemical ID
- DTXSID6041844
- DTXCIDUS EPA compound ID
- DTXCID4021844
- IUPAC
- (3R,3aR,5R,6R,6aR)-3,5,6-Trihydroxytetrahydrofuro[3,2-b]furan-2(3H)-one (non-preferred name)
- Molecular formula
- C6H8O6
- Molecular weight
- 176.124 g/mol
Measured properties
- Appearance
- Liquid
- Colour
- white
- Melting/freezing point
- 172~175 ℃ (est.)
- Initial boiling point and range
- 403.5 ℃(est.)
- Flash point
- 174.9 ℃(est.)
- Molecular weight
- 176.14
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Humectant3
- Softener and conditioner2
Source: US EPA CompTox dashboard
Related literature
- [Metabolic pathway of D-glucaric acid synthesis from D-glucuronolactone in the skin. 1. D-glucaric acid and D-glucuronolactone dehydrogenase activities in the human skin--feedback mechanism of beta-glucuronidase]. · 1972
- Improvement of Overall Skin Condition in Acne and Oily Prone Skin With an Amino Acid Cleanser Containing Salicylic Acid, Glucuronolactone, and Ceramides · 2026
- [Metabolic pathway of D-glucaric acid synthesis from D-glucuronolactone in the skin. II. Identification of the intermediates in D-glucuronolactone D-glucaric acid metabolism]. · 1972
- 皮膚におけるD-Glucuronolactone Dehydrogenaseの組織化学的研究 · 1971
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata 2 3