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Ingredients

Ingredient Dictionary

GLUTAMINE

L-glutamine is an optically active form of glutamine having L-configuration.

Molecular structure

How much products actually contain

2 products state the amountmedian 0.16%

  • under 0.01% 1
  • 0.01–0.1% 0
  • 0.1–1% 1
  • 1% or more 0

Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.

Of the products containing it, 22 list it before the 1% line and 83 after it (usually 1% or less).

Products using this ingredient

12 of 104 confirmed · likeliest to carry enough first · See all 104

Definition

L-glutamine is an optically active form of glutamine having L-configuration. It has a role as a micronutrient, a nutraceutical, an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, a glutamine and a proteinogenic amino acid. It is a conjugate base of a L-glutaminium. It is a conjugate acid of a L-glutaminate. It is an enantiomer of a D-glutamine. It is a tautomer of a L-glutamine zwitterion.

Source: PubChem

US FDA substance register · UNII 0RH81L854J · registered name Glutamine · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Reduces staticANTISTATICKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGSoftens hairHAIR CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name グルタミン: 本品は、次の化学式で表されるアミノ酸である。

Source: JCIA labelling names (Japan)

Names & identifiers

GLUTAMINEINCI글루타민Korean label name (MFDS standard)L-GlutamineSynonymグルタミンJapanese labelling name
CAS No.chemical registry number
56-85-9
EC No.EU chemical inventory number
200-292-1
DTXSIDUS EPA chemical ID
DTXSID1023100
DTXCIDUS EPA compound ID
DTXCID503100
IUPAC
L-Glutamine
Molecular formula
C5H10N2O3
Molecular weight
146.146 g/mol

Measured properties

Appearance
Opaque solid, [Merck Index] White powder, [Sigma-Aldrich MSDS] · Solid
Melting point
185.5 dec °C · 184-185 °C (decomposes)
Solubility
41300 mg/L (at 25 °C) · In water, 41,300 mg/L at 25 °C
Density
1.364 g/cu cm
Stability
Stable under recommended storage conditions.
pH
pH = 5-6 at 14.6 g/L at 25 °C
Dissociation constant
2.17 · pK1 = 2.17, pK2 = 9.13
Colour
white
Odour
odourless
Melting/freezing point
185 ℃
Initial boiling point and range
355 ℃
Vapour pressure
0.000000019 ㎜Hg
Water solubility
50000 ppm (at 30℃)
Relative density
1.364
n-Octanol/water partition coefficient (Kow)
-3.64
Decomposition temperature
185-186 ℃
Molecular weight
146.17

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Flavouring and nutrient4
  • Softener and conditioner2
  • Anti-static agent1

Source: US EPA CompTox dashboard

Related literature

Linked databases 20