L-glutamine is an optically active form of glutamine having L-configuration.
How much products actually contain
2 products state the amountmedian 0.16%
- under 0.01% 1
- 0.01–0.1% 0
- 0.1–1% 1
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 22 list it before the 1% line and 83 after it (usually 1% or less).
Products using this ingredient
12 of 104 confirmed · likeliest to carry enough first · See all 104
ROUND LABROUND LAB Soybean QLA Barrier Cream 80ml0.16% stated
CelltiaraArgan Oil Damage Control Shampoo
IDRRRestore Treatment
PARKJUN BEAUTY LABLPP Ceramide Hard Hair Curl Cream 150ml (Salon Curling Essence)
KlardieCell-Up Diamond Solution
HAIRPLUSProtein Bond Water Essence 200ml 2-Pack
LAVIENLAVIEN Medinic Line EGF Micro Pin Ampoule
OGANACELLBio Actiome Sunscreen
PARKJUN BEAUTY LABPPT Protein Treatment 250
HAIRPLUSProtein Bond Ampoule Essence 150ml Wiggle Wiggle Limited Edition
HAIRPLUSProtein Bond Ampoule Modern Peach 70ml 2-Pack
PARKJUN BEAUTY LABLPP Leave-In Treatment 200ml Damaged Hair Pack
Definition
L-glutamine is an optically active form of glutamine having L-configuration. It has a role as a micronutrient, a nutraceutical, an EC 1.14.13.39 (nitric oxide synthase) inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, a glutamine and a proteinogenic amino acid. It is a conjugate base of a L-glutaminium. It is a conjugate acid of a L-glutaminate. It is an enantiomer of a D-glutamine. It is a tautomer of a L-glutamine zwitterion.
Source: PubChem
US FDA substance register · UNII 0RH81L854J · registered name Glutamine · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name グルタミン: 本品は、次の化学式で表されるアミノ酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 56-85-9
- EC No.EU chemical inventory number
- 200-292-1
- DTXSIDUS EPA chemical ID
- DTXSID1023100
- DTXCIDUS EPA compound ID
- DTXCID503100
- IUPAC
- L-Glutamine
- Molecular formula
- C5H10N2O3
- Molecular weight
- 146.146 g/mol
Measured properties
- Appearance
- Opaque solid, [Merck Index] White powder, [Sigma-Aldrich MSDS] · Solid
- Melting point
- 185.5 dec °C · 184-185 °C (decomposes)
- Solubility
- 41300 mg/L (at 25 °C) · In water, 41,300 mg/L at 25 °C
- Density
- 1.364 g/cu cm
- Stability
- Stable under recommended storage conditions.
- pH
- pH = 5-6 at 14.6 g/L at 25 °C
- Dissociation constant
- 2.17 · pK1 = 2.17, pK2 = 9.13
- Colour
- white
- Odour
- odourless
- Melting/freezing point
- 185 ℃
- Initial boiling point and range
- 355 ℃
- Vapour pressure
- 0.000000019 ㎜Hg
- Water solubility
- 50000 ppm (at 30℃)
- Relative density
- 1.364
- n-Octanol/water partition coefficient (Kow)
- -3.64
- Decomposition temperature
- 185-186 ℃
- Molecular weight
- 146.17
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient4
- Softener and conditioner2
- Anti-static agent1
Source: US EPA CompTox dashboard
Related literature
- Topical Effect of Glutamine for Colorectal Anastomosis · 2015
- Glutamine and glutamine synthetase immunoreactivities in Schwann cells of the rat glabrous skin · 2008
- SNAT1 (SLC38A1) Is Not the Main Glutamine Transporter in Melanoma, but Controls Metabolism via Glutamine-Dependent Activation of P62 (SQSTM1)/cMYC-Axis · 2026
- Inborn error of amino acid synthesis: Human glutamine synthetase deficiency · 2006
- Glutamine for childhood malnutrition: is it needed? · 2005
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata 2