Glutathione is a tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
How much products actually contain
102 products state the amountmedian 0.01%
- under 0.01% 51
- 0.01–0.1% 29
- 0.1–1% 14
- 1% or more 8
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 194 list it before the 1% line and 612 after it (usually 1% or less).
Products using this ingredient
12 of 803 confirmed · likeliest to carry enough first · See all 803
PurcellPurcell 88 Billion/mL Glutathione Flexible Liposome Tone-Up Ampoule 20ml5% stated
FROM THE SKINGlutathione Collagen Eye Cream3% stated
FROM THE SKINFROM THE SKIN Glutathione Collagen Eye Cream (Refill)3% stated
ChardeGlutathione Toning Eye Cream3% stated
TOSOWOONGGlutathione Ampoule2% stated
teeheeheeGlutathione Glow Barrier Serum1.2% stated
Manyo FactoryGlutathione 7 Dark Spot Serum1% stated
Manyo FactoryManyo Factory Glutathione 7 Dark Spot Serum1% stated
MEDIPEELMEDIPEEL Bio Intense Glutathione White Ampoule 2.0 30ml0.6% stated
TOSOWOONGArbutin 7% Glutathione Cream0.5% stated
SKIN&LABGlutathione Ampoule Toner 200ml0.3% stated
JUDIMERGlutathione Double X Ampoule Mist0.1% stated
Definition
Glutathione is a tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. It has a role as a geroprotector, an antioxidant, a cofactor, a mouse metabolite, an Escherichia coli metabolite, a human metabolite and a skin lightening agent. It is a thiol, a tripeptide and a L-cysteine derivative. It is a conjugate acid of a glutathionate(1-).
Source: PubChem
US FDA substance register · UNII GAN16C9B8O · registered name Glutathione · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name グルタチオン: 本品は、グルタミン酸（＊）とシステイン（＊）及びグリシン（＊）からなるトリペプチドであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 70-18-8
- EC No.EU chemical inventory number
- 200-725-4
- DTXSIDUS EPA chemical ID
- DTXSID6023101
- DTXCIDUS EPA compound ID
- DTXCID903101
- IUPAC
- L-gamma-Glutamyl-L-cysteinylglycine
- Molecular formula
- C10H17N3O6S
- Molecular weight
- 307.32 g/mol
Measured properties
- Appearance
- Solid, [Merck Index] White powder, [Sigma-Aldrich MSDS] · Solid
- Melting point
- 195 °C
- Solubility
- 292.5 mg/mL
- Colour
- white
- Melting/freezing point
- 195 ℃
- Vapour density
- 10.61
- n-Octanol/water partition coefficient (Kow)
- -5.41 (est.)
- Molecular weight
- 307.32348
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Reducing agent3
- Fragrance1
Source: US EPA CompTox dashboard
Related literature
- Engineering Escherichia coli for efficient glutathione production. · 2024
- Elucidation of Plasma-induced Chemical Modifications on Glutathione and Glutathione Disulphide · 2017
- Elucidation of Plasma-induced Chemical Modifications on Glutathione and Glutathione Disulphide · 2017
- A regulatory review for products containing glutathione · 2016
- Application of Glutathione and the Study Progress of Glutathione by Enzymatic Method · 2005
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese