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Ingredientes

Diccionario de ingredientes

GLYCERYL THIOGLYCOLATE

Glyceryl monothioglycolate is a thioglycolate ester resulting from esterification of thioglycolic acid with glycerol.

Estructura molecular

Definición

Registro de sustancias de la FDA (EE. UU.) · UNII 0FWE72AF2P · nombre registrado GLYCERYL MONOTHIOGLYCOLATE · mezcla

Fuente: Identificador único de ingredientes de la FDA (UNII)

Glyceryl monothioglycolate is a thioglycolate ester resulting from esterification of thioglycolic acid with glycerol. As a component of developer solutions in permanent wave products, it is the second most frequent allergen in hairdressers and avoidance of acid permanent waves is mandatory. It has a role as an allergen.

Fuente: PubChem

Mercaptoacetic acid, monoester with propane-1,2,3-triol

Funciones cosméticas

Riza o alisa el cabelloHAIR WAVING OR STRAIGHTENING

Referencias de seguridad y regulación

Restringido
China

Fuente: Información regulatoria cosmética del MFDS (Corea)

Argentina · Brasil

  • Field of application and/or use : Products for straightening or waving hair: 1. General use 2. Professional use
  • Maximum concentration permitted at final product : 1. 8% ready to use pH 6 to 9,5 2.11% ready to use pH 6 to 9.5 The percentages are calculated as thioglycolic acid
  • Other limitations and requirements : 1) and 2) In the USAGE must consist obligatorily the following information: - May cause sensitization by skin contact. - Avoid contact with eyes. - In case of contact with eyes, rinse immediately and thoroughly with water and consult a doctor. - Wear suitable gloves
  • Use conditions and warnings that must appear on the label : 1) and 2) Contains thioglycolate Follow the instructions Keep out of reach of children. For professional use only (if applicable)

ASEAN

  • Field of application and/or use : Hair waving or straightening products: 1. General use 2. Professional use
  • Maximum authorised concentration in the finished cosmetic product : 1. 8% ready for use at pH 6-9.5 2. 11% ready for use at pH 6-9.5 Percentages calculated as thioglycolic acid.
  • Other limitations and requirements : The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • May cause sensitisation in the event of skin contact. • Avoid contact with eyes. • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves.
  • Conditions of use and warning which must be printed on the labels : • Contains thioglycolate. • Follow the instructions. • Keep out of reach of children. • For professional use only.

Unión Europea

  • Product Type, body parts : Hair waving or straightening products
  • Maximum concentration in ready for use preparation : (a) 8% (b) 11% The abovementioned percentages are calculated as thioglycollic acid
  • Other : (a) General use ready for use pH 6 to 9.5 (b) Professional use ready for use pH 6 to 9.5
  • Wording of conditions of use and warnings : Conditions of use: (a) (b) May cause sensitization in the event of skin contact Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice Wear suitable gloves Warnings: Contains thioglycolate Follow the instructions Keep out of reach of children (b) For professional use only

Fuente: Información regulatoria cosmética del MFDS (Corea)

Sin clasificación en la lista GHS de sustancias tóxicas de Corea

Fuente: Registro GHS de sustancias tóxicas de Corea (NIER)

Lista de ingredientes cosméticos de Health Canada · prohibido en cosméticos

Fuente: Lista de ingredientes restringidos de Health Canada

Restriction III/2b

Fuente: Lista de ingredientes CosIng (UE)

Reviewed by CIR: Final Report on the Safety Assessment of Ammonium and Glyceryl Thioglycolates and Thioglycolic Acid

Fuente: Cosmetic Ingredient Review (CIR, EE. UU.)

Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid

Fuente: Cosmetic Ingredient Review (CIR, EE. UU.)

Más datos: nombres, identificadores, propiedades, ensayos y literatura

Nombres y definiciones oficiales

Nombre de etiquetado de la JCIA チオグリコール酸グリセリル: 本品は、チオグリコール酸(*)とグリセリン(*)のモノエステルであり、次の化学式で表される。

Fuente: Nombres de etiquetado de la JCIA (Japón)

Nombres e identificadores

GLYCERYL THIOGLYCOLATEINCI글리세릴티오글라이콜레이트Nombre en etiquetas coreanas (estándar MFDS)Acetic acid, mercapto-, monoester with 1,2,3-propanetriolSinónimoチオグリコール酸グリセリルNombre de etiquetado japonés
CAS No.número de registro químico
30618-84-9
EC No.número de inventario químico de la UE
250-264-8
DTXSIDidentificador químico de la EPA (EE. UU.)
DTXSID2027965

Propiedades medidas

Aspecto
Colorless viscous liquid with a mild sulfurous odor, [Lanza Research MSDS]

Valores medidos en la sustancia en sí, no una especificación de una materia prima comercial.

Fuente: PubChem

Para qué lo usan los productos

Usos de los 1 productos declarados ante la EPA de EE. UU. con este ingrediente. Incluye productos que no son cosméticos, así que las primeras filas son sus usos principales.

  • Hair waving or straightening (EPA)1

Fuente: Panel CompTox de la EPA

Estudios de irritación y sensibilización

Constan 6 estudios en piel y 2 en ojos.

Clasificado como muy irritante1Clasificado como bajo3

Los estudios no coinciden (la conclusión más frecuente reúne el 25%), así que no demuestran que el ingrediente sea irritante. Son ensayos de la materia prima en sí; la irritación a la cantidad de un producto terminado es otra cuestión.

Ver los 8 estudios
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • Sh
    Skin Sensitization · Authoritative
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to

Fuente: Panel CompTox de la EPA

Literatura relacionada

Bases de datos vinculadas 19