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Ingredients

Ingredient Dictionary

GLYCIDOXYPROPYL TRIMETHOXYSILANE

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 2 list it before the 1% line and 0 after it (usually 1% or less).

Products using this ingredient

2 of 2 confirmed · likeliest to carry enough first

Definition

US FDA substance register · UNII 5K9X9X899R · registered name (3-GLYCIDOXYPROPYL)TRIMETHOXYSILANE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Cares for nailsNAIL CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name グリシドキシプロピルトリメトキシシラン: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

GLYCIDOXYPROPYL TRIMETHOXYSILANEINCI글라이시독시프로필트라이메톡시실란Korean label name (MFDS standard)Silane, trimethoxy[3-(oxiranylmethoxy)propyl]-SynonymグリシドキシプロピルトリメトキシシランJapanese labelling name
CAS No.chemical registry number
2530-83-8
EC No.EU chemical inventory number
219-784-2
DTXSIDUS EPA chemical ID
DTXSID5027489
DTXCIDUS EPA compound ID
DTXCID507489
IUPAC
Trimethoxy{3-[(oxiran-2-yl)methoxy]propyl}silane
Molecular formula
C9H20O5Si
Molecular weight
236.339 g/mol

Measured properties

Appearance
Liquid, Dry Powder · Liquid, [eChemPortal: SIDSUNEP] Clear colorless liquid, [MSDSonline]
Boiling point
290 °C @760 [mm Hg]
Density
1.065-1.075 @25 °C
Melting/freezing point
0 ℃
Initial boiling point and range
&amp, gt, 149 ℃
Flash point
130 ℃((c.c))
Evaporation rate
(&amp, gt, 1)
Vapour pressure
0.0142 ㎜Hg (at 25℃ (est.))
Water solubility
( 170g/L at 25℃ (est.))
Vapour density
8.15
Relative density
1.070 ()
n-Octanol/water partition coefficient (Kow)
-0.92 ((est.))
Auto-ignition temperature
400 ℃
Viscosity
(4 mPas)
Molecular weight
236.34

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 83 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Adhesion/cohesion promoter48
  • Chemical reaction regulator9
  • Hardener6
  • Processing aids not otherwise specified3
  • Viscosity modifier2
  • Thickening agent2
  • Polymerization promoter2
  • Solvent2
9 other uses
  • Softener and conditioner1
  • Film former1
  • Sealant (barrier)1
  • Lubricating agent1
  • Wetting agent (non-aqueous)1
  • Intermediate1
  • Surface modifier1
  • Plating agent1
  • Corrosion inhibitor1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

Source: US EPA CompTox dashboard

Related literature

Linked databases 17