Ingredient Dictionary

GLYCOL DIMETHACRYLATE

Ethylene glycol dimethacrylate is the enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol.

Definition

Ethylene glycol dimethacrylate is the enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol. It has a role as a cross-linking reagent, an allergen and a polymerisation monomer. It is functionally related to a methacrylic acid and an ethylene glycol.

Source: PubChem

US FDA substance register · UNII 7BK5G69305 · registered name GLYCOL DIMETHACRYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Glycol Dimethacrylate is the organic compound

Cosmetic roles

Cares for nailsNAIL CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジメタクリル酸グリコール: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

GLYCOL DIMETHACRYLATEINCI글라이콜다이메타크릴레이트Korean label name (MFDS standard)2-Propenoic acid, 2-methyl-, 1,2-ethanediyl esterSynonymジメタクリル酸グリコールJapanese labelling name

CAS No.chemical registry number: 97-90-5
EC No.EU chemical inventory number: 202-617-2
DTXSIDUS EPA chemical ID: DTXSID1026615
DTXCIDUS EPA compound ID: DTXCID106615

IUPAC: Ethane-1,2-diyl bis(2-methylprop-2-enoate)
Molecular formula: C10H14O4
Molecular weight: 198.218 g/mol

Measured properties

Appearance: Liquid · Colorless liquid, [ICSC] Light yellow liquid, [Aldrich MSDS]
Boiling point: 260 · 260 °C
Melting point: -40 °C
Solubility: > 10% in benzene · > 10% in ethanol
Density: 1.055 at 20 °C/20 °C · Relative density (water = 1): 1.05
Viscosity: 3.03 mm²/s at 20 °C
Colour: colourless
Melting/freezing point: -40 ℃
Initial boiling point and range: 260 ℃
Flash point: 101 ℃
Vapour pressure: 478 ㎩ ( 20℃)
Water solubility: 581 ㎎/ℓ ( 25℃)
Vapour density: 6.8
Relative density: 1.05
n-Octanol/water partition coefficient (Kow): 1.87
Molecular weight: 198.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Monomers6
Hardener3
Intermediate2
Catalyst2
Photosensitive agent1
Film former1
Softener and conditioner1
Sealant (barrier)1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 2 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: The test was performed according to Magnusson B and Kligman AM (1970) in: Allergic Contact Dermatitis in the Guinea Pig. Thomas, Springfield, III
Classification not possible
Skin Irritation · Screening
Sh
Skin Sensitization · Authoritative
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: according to Appraisal of the Safety of Chemicals in foods, drugs and cosmetics, FDA Draize (1959) according to
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Skin Sens. 1
Skin Sensitization · Authoritative
Category 1
Skin Sensitization · Screening
Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) now OECD 429 (LLNA local lymph node assay)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: according to Appraisal of the Safety of Chemicals in foods, drugs and cosmetics, FAD Draize (1959) according to
Classification not possible
Eye Irritation · Screening