Ethylene glycol dimethacrylate is the enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol.
定义
Ethylene glycol dimethacrylate is the enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol. It has a role as a cross-linking reagent, an allergen and a polymerisation monomer. It is functionally related to a methacrylic acid and an ethylene glycol.
来源: PubChem
美国FDA 物质登记 · UNII 7BK5G69305 · 登记名称 GLYCOL DIMETHACRYLATE · 单一化学物质
Glycol Dimethacrylate is the organic compound
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 ジメタクリル酸グリコール: 本品は、次の化学式で表される有機化合物である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 97-90-5
- EC No.欧盟化学品目录编号
- 202-617-2
- DTXSID美国EPA化学品编号
- DTXSID1026615
- DTXCID美国EPA化合物编号
- DTXCID106615
- IUPAC
- Ethane-1,2-diyl bis(2-methylprop-2-enoate)
- 分子式
- C10H14O4
- 分子量
- 198.218 g/mol
实测物性
- 性状
- Liquid · Colorless liquid, [ICSC] Light yellow liquid, [Aldrich MSDS]
- 沸点
- 260 · 260 °C
- 熔点
- -40 °C
- 溶解性
- > 10% in benzene · > 10% in ethanol
- 密度
- 1.055 at 20 °C/20 °C · Relative density (water = 1): 1.05
- 黏度
- 3.03 mm²/s at 20 °C
- 颜色
- 无色
- 熔点/凝固点
- -40 ℃
- 初沸点和沸程
- 260 ℃
- 闪点
- 101 ℃
- 蒸气压
- 478 ㎩ ( 20℃)
- 溶解度
- 581 ㎎/ℓ ( 25℃)
- 蒸气密度
- 6.8
- 比重
- 1.05
- 正辛醇/水分配系数（Kow）
- 1.87
- 分子量
- 198.2
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 17 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Monomers6
- Hardener3
- Intermediate2
- Catalyst2
- Photosensitive agent1
- Film former1
- Softener and conditioner1
- Sealant (barrier)1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 8 项、眼部试验 2 项。
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 10 项试验
- High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: The test was performed according to Magnusson B and Kligman AM (1970) in: Allergic Contact Dermatitis in the Guinea Pig. Thomas, Springfield, III - Classification not possible
Skin Irritation · Screening - Sh
Skin Sensitization · Authoritative - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: according to Appraisal of the Safety of Chemicals in foods, drugs and cosmetics, FDA Draize (1959) according to - Category 6.5B (Category 1)
Skin Sensitization · Read Across - Skin Sens. 1
Skin Sensitization · Authoritative - Category 1
Skin Sensitization · Screening - Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) now OECD 429 (LLNA local lymph node assay) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: according to Appraisal of the Safety of Chemicals in foods, drugs and cosmetics, FAD Draize (1959) according to - Classification not possible
Eye Irritation · Screening
来源: 美国EPA CompTox
相关文献
- Bacterial Nanocellulose and Its Surface Modification by Glycidyl Methacrylate and Ethylene Glycol Dimethacrylate. Incorporation of Vancomycin and Ciprofloxacin · 2019
- Designing and In Vitro Characterization of pH-Sensitive Aspartic Acid-Graft-Poly(Acrylic Acid) Hydrogels as Controlled Drug Carriers · 2022
- Assessment of the different skin sensitization potentials of irritants and allergens as single substances and in combination using the KeratinoSens assay · 2020
- Occupational contact dermatitis in a manicurist · 2019
- Final Report of the Cosmetic Ingredient Review Expert Panel Safety Assessment of Polymethyl Methacrylate (PMMA), Methyl Methacrylate Crosspolymer, and Methyl Methacrylate/Glycol Dimethacrylate Crosspolymer · 2011