Definition
US FDA substance register · UNII YRZ676PGU6 · registered name GLYCOLIDE · single chemical substance
Glycolide is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name グリコリド: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 502-97-6
- EC No.EU chemical inventory number
- 207-954-9
- DTXSIDUS EPA chemical ID
- DTXSID8060115
- DTXCIDUS EPA compound ID
- DTXCID1040790
- IUPAC
- 1,4-Dioxane-2,5-dione
- Molecular formula
- C4H4O4
- Molecular weight
- 116.072 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Melting/freezing point
- 48~86 ℃
- Vapour pressure
- 0.14 ㎩ (25℃)
- Vapour density
- 1.613 g/㎤
- n-Octanol/water partition coefficient (Kow)
- 0.81 (log Pow, 25℃)
- Decomposition temperature
- &, gt, 298 ℃
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Intermediate1
- Humectant1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (adopted 1992-07-17) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) (dated 1992-07-31) according to - SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Use of Stacked Layers of Electrospun L-Lactide/Glycolide Co-Polymer Fibers for Rapid Construction of Skin Sheets · 2021
- Injection molding for manufacturing of solid poly(l-lactide-co-glycolide) microneedles · 2021
- Carbol fuchsin stain enhances detection of poly‐(d, l‐lactide‐co‐glycolide) microspheres in exenatide extended‐release cutaneous injection‐site foreign body reaction · 2021
- Poly(d,l-lactide-co-glycolide) (PLGA) Nanoparticles Loaded with Proteolipid Protein (PLP)—Exploring a New Administration Route · 2020
- Drug-loaded poly(d,l-lactide-co-glycolide) microspheres as treatment for allergic contact dermatitis in mice model · 2017
Linked databases 15
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese