Gloshell
Ingredients
All ingredients

Ingredient Dictionary

GLYOXAL

Glyoxal is the dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons.

Korean limit
0.01%
Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 6 list it before the 1% line and 31 after it (usually 1% or less).

Products using this ingredient

12 of 37 confirmed · likeliest to carry enough first · See all 37

Definition

Glyoxal is the dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons. It has a role as a pesticide, a plant growth regulator, an agrochemical and an allergen.

Source: PubChem

US FDA substance register · UNII 50NP6JJ975 · registered name Glyoxal · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMINGInhibits microbial growthANTIMICROBIAL

Safety & regulatory references

Restricted
United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

Argentina · Brazil

  • Maximum concentration permitted at final product : 100 mg/kg

ASEAN

  • Maximum authorised concentration in the finished cosmetic product : 100mg/kg

South Korea

  • Maximum concentration : 0.01%

European Union

  • Maximum concentration in ready for use preparation : 100 mg/kg

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 194 · maximum concentration 100 mg/kg

Source: EU restricted substances (Annex III)

Restriction III/194

Source: EU CosIng ingredient list

Reviewed by CIR: Glyoxal

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Amended Final Report on the Safety Assessment of Glyoxal

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Glyoxal (Amended final report 6/97)

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name グリオキサール: 本品は、次の化学式で表されるアルデヒドである。

Source: JCIA labelling names (Japan)

Names & identifiers

GLYOXALINCI글라이옥살Korean label name (MFDS standard)EthanedialSynonymグリオキサールJapanese labelling name
CAS No.chemical registry number
107-22-2
EC No.EU chemical inventory number
203-474-9
DTXSIDUS EPA chemical ID
DTXSID5025364
DTXCIDUS EPA compound ID
DTXCID505364
IUPAC
Oxaldehyde
Molecular formula
C2H2O2
Molecular weight
58.036 g/mol

Measured properties

Appearance
Glyoxal appears as yellow crystals melting at15 °C. Hence often encountered as a light yellow liquid with a weak sour odor. Vapor has a green color and burns with a violet flame. · CBI, Dry Powder, Liquid
Odour
Mild odor
Boiling point
124 °F at 776 mmHg (NTP, 1992) · 51 °C at 776 mm Hg
Melting point
59 °F (NTP, 1992) · 15 °C for pure glyoxal and approximately -10 °C for the 40% solution
Solubility
greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) · Sol in anhydrous solvents
Density
1.29 at 68 °F (liquid,40% solution) (USCG, 1999) - Denser than water, will sink · 1.14 g/cu cm at 20 °C
pH
pH of 40% aqueous solution = 2.1 to 2.7 · 2.4
Melting/freezing point
-14 ℃
Initial boiling point and range
104 ℃
Flash point
100 ℃
Vapour pressure
2.4 ㎜Hg (20℃)
Water solubility
100 g/100㎖ (20℃)
Vapour density
1.27
Relative density
1.27
n-Octanol/water partition coefficient (Kow)
-0.85
Auto-ignition temperature
285 ℃
Molecular weight
58.02

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Fragrance3
  • Intermediate2
  • Surfactant (surface active agent)2
  • Processing aids not otherwise specified2
  • Hardener2
  • Chemical reaction regulator2
  • Monomers2
  • Biocide2
6 other uses
  • Surface modifier1
  • Fuel agents1
  • Viscosity modifier1
  • Film former1
  • Cleaning agent1
  • Preservative1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

12 skin studies and 5 eye studies are on record.

Classed as moderate2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 17 studies
  • Category 2
    Skin Irritation · Screening
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Skin sensitization - Category 1
    Skin Sensitization · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Skin irritation - category 2
    Skin Irritation · Screening
  • Skin sensitisation - category 1
    Skin Sensitization · Screening
  • Skin Sens. 1
    Skin Sensitization · Authoritative
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • Category 1
    Skin Sensitization · Screening
  • Skin corrosion/irritation - Category 2
    Skin Irritation · Screening
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Serious eye damage/eye irritation - Category 2
    Eye Irritation · Screening
  • Eye irritation - category 2A
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative
  • Category 2A
    Eye Irritation · Screening

Source: US EPA CompTox dashboard

Related literature

Linked databases 27

Community

Post a question: Gloshell AI answers first, then other members join in.