Guaiazulene is a sesquiterpene.
How much products actually contain
23 products state the amountmedian 0.01%
- under 0.01% 9
- 0.01–0.1% 13
- 0.1–1% 1
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 18 list it before the 1% line and 91 after it (usually 1% or less).
Products using this ingredient
12 of 109 confirmed · likeliest to carry enough first · See all 109
TheradermAzulene Ampoule0.5% stated
NEOGENNeogen Surmedic+ Azulene Soothing Ampoule 80ml0.0075% stated
NEOGENSurmedic+ Azulene Soothing Mousse Toner0.001% stated
NEOGENNeogen Surmedic+ Azulene Soothing Mousse Toner 110ml0.001% stated
MUCIPIMama & Me Soft Oil
CellFusionCFirst Cure Serum
CellFusionCCellFusionC First Cure Serum
S.NATUREAqua Oasis Blue Calming Ampoule
NEOGENNeogen Surmedic+ Azulene UV Tone-Up Sun Primer 50ml SPF50+ PA++++
Banila CoClean It Zero Calming Cleansing Balm 100ml
SidmoolACBYE Darkspot Recovery Gel
ENOUGHUltra Extend Collagen Pro Marine Ampoule
Definition
Guaiazulene is a sesquiterpene. It derives from a hydride of a guaiane.
Source: PubChem
US FDA substance register · UNII 2OZ1K9JKQC · registered name GUAIAZULENE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted
- South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Field of application and/or use : Dye Substances allowed for all kinds of products, except those applied in the eye area.
ASEAN
- Field of application : Colouring agents allowed in all cosmetic products except those intended to be applied in the vicinity of eyes, in particular eye make-up and eye make-up remover.
United States
- Eye Area : No
- Generally (Includes Lipsticks) : No
- External Use : Yes
Source: MFDS (Korea) cosmetic regulatory information
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name グアイアズレン: 本品は、次の化学式で表される環式炭化水素である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 489-84-9
- EC No.EU chemical inventory number
- 207-701-2
- DTXSIDUS EPA chemical ID
- DTXSID7045996
- DTXCIDUS EPA compound ID
- DTXCID5025996
- IUPAC
- 1,4-Dimethyl-7-(propan-2-yl)azulene
- Molecular formula
- C15H18
- Molecular weight
- 198.309 g/mol
Measured properties
- Appearance
- Solid
- Boiling point
- 152.00 to 154.00 °C. @ 7.00 mm Hg
- Melting point
- 31.5 °C
- Solubility
- 0.000664 mg/mL at 25 °C
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance4
- Biocide2
- Dye2
Source: US EPA CompTox dashboard
Related literature
- Effects of Guaiazulene on Lipid Peroxidation and Antioxidant Defense System in Drosophila melanogaster · 2023
- Guaiazulene and related compounds: A review of current perspective on biomedical applications. · 2023
- Avobenzone, Guaiazulene and Tioxolone identified as potent autophagy inducers in a high-throughput image based screen for autophagy flux · 2022
- Guaiazulene Triggers ROS-Induced Apoptosis and Protective Autophagy in Non-small Cell Lung Cancer · 2021
- EFFECTS OF GUAIAZULENE ON IN VITRO CULTURE OF BOVINE ZYGOTES, AND ON mRNA TRANSCRIPTS RELATED TO EMBRYO QUALITY · 2009
Linked databases 22
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA color additives
- US FDA prohibited and restricted ingredients
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese