What is this ingredient?

미국 FDA 물질 등록 · UNII V3394X3G2W · 등록명 GUANIDINE CARBONATE · 단일 화학물질

All ingredients

Ingredient Dictionary

GUANIDINE CARBONATE

Definition

US FDA substance register · UNII V3394X3G2W · registered name GUANIDINE CARBONATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGKeeps pH steadyBUFFERING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 炭酸グアニジン: 本品は、グアニジンの炭酸塩であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

GUANIDINE CARBONATEINCI구아니딘카보네이트Korean label name (MFDS standard)Carbonic acid, compound with guanidine (1:2)Synonym炭酸グアニジンJapanese labelling name

CAS No.chemical registry number: 100224-74-6
CAS No.chemical registry number: 593-85-1
EC No.EU chemical inventory number: 209-813-7
DTXSIDUS EPA chemical ID: DTXSID0029189
DTXCIDUS EPA compound ID: DTXCID109189

IUPAC: Carbonic acid--guanidine (1/2)
Molecular formula: C3H12N6O3
Molecular weight: 180.168 g/mol

Measured properties

Appearance: Dry Powder · White crystalline solid, [Sigma-Aldrich MSDS]
Colour: white
Melting/freezing point: &amp, gt, 190 ℃
Flash point: 197 ℃
Vapour pressure: (2.15E-014mmHg, 25℃)
Water solubility: 45 g/100㎖(at 20 ℃)
Vapour density: 6.2
Relative density: 1.251 (at 20 ℃)
Auto-ignition temperature: 530 ℃
Decomposition temperature: (195-199℃)
Molecular weight: 180.17

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

pH regulating agent3
Softener and conditioner2
Hair waving or straightening (EPA)1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 4 eye studies are on record.

Classed as low4

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies

Category 6.3A (Category 2)
Skin Irritation · Read Across
Classification not possible
Skin Sensitization · Screening
Classification not possible
Skin Irritation · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Classification not possible
Eye Irritation · Screening
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to