定义
美国FDA 物质登记 · UNII 2TXI2V75J2 · 登记名称 MONOGUANIDINE PHOSPHATE · 单一化学物质
化妆品中的作用
保持肌肤良好状态(CosIng 泛分类)SKIN CONDITIONING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
GUANIDINE PHOSPHATEINCI구아니딘포스페이트韩国标示名称(食药处标准名)
- CAS No.化学物质登记号
- 1763-07-1
- CAS No.化学物质登记号
- 5423-22-3
- EC No.欧盟化学品目录编号
- 217-176-1
- EC No.欧盟化学品目录编号
- 226-551-9
- DTXSID美国EPA化学品编号
- DTXSID201036309
- DTXCID美国EPA化合物编号
- DTXCID601367304
- IUPAC
- (Diaminomethylidene)ammonium dihydrogen phosphate
- 分子式
- CH8N3O4P
- 分子量
- 157.066 g/mol
实测物性
- 性状
- 固体
- 熔点/凝固点
- 125.8 ℃
- 蒸气压
- &, lt, 0.015 ㎩ (at 20 °C, OECD TG 104)
- 溶解度
- 0.95~1 g/100㎖ (at 25 °C, OECD TG 105)
- 正辛醇/水分配系数(Kow)
- &, lt, -3.48 ((OECD Guideline 107))
- 自燃温度
- &, gt, 400 ℃ ((EU Method A.16))
- 分子量
- 157.06
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
刺激与致敏试验记录
记录有皮肤试验 1 项、眼部试验 1 项。
归类为低1 项
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 2 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Japanese Ministry of Agriculture, Forestry and Fisheries (JMAFF), 2011, including the most recent partial revisions. according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to
来源: 美国EPA CompTox
相关文献
- Mitigation of environmental impact caused by flame retardant textile finishing chemicals · 2020
- Eye irritation tests of polyhexamethylene guanidine phosphate (PHMG) and chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a tissue model of reconstructed human cornea-like epithelium · 2019
- Prediction of the skin sensitization potential of polyhexamethylene guanidine phosphate, oligo(2-(2-ethoxy)ethoxyethyl) guanidinium chloride, triclosan, and mixtures of these compounds with the excipient propylene glycol through the local lymph node assay: BrdU-FCM · 2019
- Safety study, anti-inflammatory and antioxidant action of drug caramel with polyhexamethylene guanidine phosphate · 2016
- Humidifier disinfectant lung injury, how do we approach the issues? · 2016