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Ingredients

Ingredient Dictionary

HC YELLOW NO. 4

HC Yellow No.

Molecular structure

Definition

US FDA substance register · UNII 0N97D5G157 · registered name HC YELLOW NO. 4 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

HC Yellow No. 4 is a C-nitro compound.

Source: PubChem

HC Yellow No. 4 is the hair color that conforms to the formula:

Cosmetic roles

Dyes hairHAIR DYEING

Safety & regulatory references

Restricted
Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

ASEAN

  • Field of application and/or use : Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
  • Maximum authorised concentration in the finished cosmetic product : 1.5%
  • Other limitations and requirements : • Do not use with nitrosating agents • Maximum nitrosamine content: 50μg/kg • Keep in nitrite-free containers The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : Do not use to dye eyelashes or eyebrows

China

  • Maximum concentration : 1.5%

European Union

  • Product Type, body parts : Hair dye substance in non-oxidative hair dye products
  • Maximum concentration in ready for use preparation : 1,5%
  • Other : - Do not use with nitrosating agents - Maximum nitrosamine content: 50 micrograme/Kg - Keep in nitrite-free containers

Source: MFDS (Korea) cosmetic regulatory information

EU Cosmetics Regulation, Annex III (restricted substances), entry 253 · maximum concentration 1,5 % · applies to Hair dye substance in non-oxidative hair dye products

Source: EU restricted substances (Annex III)

EU Cosmetics Regulation, Annex III (restricted substances), entry 253 · maximum concentration 1,5% · applies to Hair dye substance in non-oxidative hair dye products

Source: EU restricted substances (Annex III)

Restriction Annex III/253 · SCCS opinion: Opinion on HC Yellow No. 4

Source: EU CosIng ingredient list

Reviewed by CIR: 40th Anniversary Overview and Rereview Summaries From 2011 to 2015

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of HC Yellow No. 4

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name HC黄4: 本品は、次の化学式で表される頭髪用染料である。

Source: JCIA labelling names (Japan)

Names & identifiers

HC YELLOW NO. 4INCI에치씨황색4호Korean label name (MFDS standard)N, O-Di(hydroxyethyl)-2-amino-5-nitrophenolSynonymHC YELLOW NO.4SynonymHC黄4Japanese labelling name
CAS No.chemical registry number
59820-43-8
EC No.EU chemical inventory number
428-840-7
DTXSIDUS EPA chemical ID
DTXSID6021458
DTXCIDUS EPA compound ID
DTXCID601458
IUPAC
2-[2-(2-Hydroxyethoxy)-4-nitroanilino]ethan-1-ol
Molecular formula
C10H14N2O5
Molecular weight
242.231 g/mol

Measured properties

Appearance
Canary yellow fluffy powder. (NTP, 1992) · Bright yellow solid, [CAMEO]
Melting point
284 to 291 °F (NTP, 1992)
Solubility
less than 0.1 mg/mL at 68.9 °F (NTP, 1992)

Values measured on the substance itself, not a specification for a commercial raw material.

Source: PubChem

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Dye3

Source: US EPA CompTox dashboard

Related literature

Linked databases 23