Definition
US FDA substance register · UNII R79J91U341 · registered name HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: EDTA and Salts
Reviewed by CIR: Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, HEDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, and Trisodium HEDTA
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 150-39-0
- EC No.EU chemical inventory number
- 205-759-3
- DTXSIDUS EPA chemical ID
- DTXSID1059737
- DTXCIDUS EPA compound ID
- DTXCID5034858
- IUPAC
- N-{2-[Bis(carboxymethyl)amino]ethyl}-N-(2-hydroxyethyl)glycine
- Molecular formula
- C10H18N2O7
- Molecular weight
- 278.261 g/mol
Measured properties
- Appearance
- Liquid · Solid, [Hawley] White odorless powder, [MSDSonline]
- Melting point
- 288 °C (hydate) · 159 °C
- Solubility
- Insoluble in most organic solvents · In water, 480 g/L at 20 °C
- Density
- 1.285 · 1.285 @25 °C
- pH
- pH of a 1 wt% solution = 11.2
- Melting/freezing point
- 159 ℃
- Water solubility
- (40.4 % @ 20 ℃)
- Vapour density
- 9.61
- Relative density
- 1.301 (@ 20 ℃)
- n-Octanol/water partition coefficient (Kow)
- -4.65 (@ 20 ℃)
- Molecular weight
- 278.26
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Ion exchange agent2
- Chelating agent2
- Opacifer1
- Viscosity modifier1
- Filler1
- Absorbent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinIrr2
Skin Irritation · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Mineral Analysis of Dolomite Formation During Carbonate Acidizing Using Chelating Agents · 2025
- Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, HEDTA, and Trisodium HEDTA · 2002
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English