Sapienic acid is a hexadecenoic acid in which the double bond is located at position 6 (the Z-geoisomer).
Definition
US FDA substance register · UNII 6460S1EJ28 · registered name SAPIENIC ACID · single chemical substance
Sapienic acid is a hexadecenoic acid in which the double bond is located at position 6 (the Z-geoisomer). A major component of human sebaceous lipids that is involved in skin self-sterilisation and atopic dermatitis amelioration. It has a role as a metabolite, an antibacterial agent and an antipsoriatic. It is a conjugate acid of a sapienate.
Source: PubChem
Cosmetic roles
Makes skin soft and smoothSKIN CONDITIONING - EMOLLIENTKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONING
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ヘキサデセン酸: 本品は、次の化学式で表される不飽和有機酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
HEXADECENOIC ACIDINCI헥사데케노익애씨드Korean label name (MFDS standard)ヘキサデセン酸Japanese labelling name
- CAS No.chemical registry number
- 17004-51-2
- DTXSIDUS EPA chemical ID
- DTXSID50904584
- DTXCIDUS EPA compound ID
- DTXCID001333713
- IUPAC
- (6Z)-Hexadec-6-enoic acid
- Molecular formula
- C16H30O2
- Molecular weight
- 254.414 g/mol
Related literature
- Base-assisted Extraction and GC-MS analysis of Bioactive Compounds from Mango and Neem Leaves: Potential for pharmaceutic and Bioenergy applications · 2025
- Human Sebaceous Cis-6-Hexadecenoic Acid: Possible Application of an Innate Antimicrobial Substance to Cosmetic Products for Mucous Membrane · 2017
- Identification and Biosynthesis of Novel Male Specific Esters in the Wings of the Tropical Butterfly, Bicyclus martius sanaos · 2014
- Identification and Biosynthesis of Novel Male Specific Esters in the Wings of the Tropical Butterfly, Bicyclus martius sanaos · 2014
- The effect of skin fatty acids on Staphylococcus aureus · 2014
Linked databases 14
- ChEBI
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese