Galaxolide is an organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively.
How much products actually contain
No product states its amount yet.
Of the products containing it, 18 list it before the 1% line and 194 after it (usually 1% or less).
Products using this ingredient
12 of 212 confirmed · likeliest to carry enough first · See all 212
FOELLIEInner Perfume Eau de Acot
GlossierGlossier Glossier You Fleur
GlossierGlossier Glossier You Soie
philosophyphilosophy Amazing Grace Cream-To-Water Body Lotion
philosophyphilosophy Travel-Size Vanilla Hug Body & Hair Fragrance Mist
philosophyphilosophy Vanilla Hug Body & Hair Fragrance Mist
Kylie CosmeticsKylie Cosmetics Vanilla Dew Hair & Body Mist
philosophyphilosophy Pure Grace Firming Body Emulsion
Paul MitchellPaul Mitchell Dry Conditioner Spray
OUAIOUAI Hair & Body Fragrance Mist Melrose Place
OUAIOUAI Deodorant Melrose Place
OUAIOUAI Deodorant St. Barts Scent
Definition
US FDA substance register · UNII 14170060AT · registered name HEXAMETHYLINDANOPYRAN · single chemical substance
Galaxolide is an organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively. It is a synthetic musk used as a fragrance in cosmetics. It has a role as a fragrance. It is an organic heterotricyclic compound and a member of isochromenes.
Source: PubChem
Hexamethylindanopyran is the organic compound that conforms to the formula
Cosmetic roles
Safety & regulatory references
European Union
- Other : The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products
Source: MFDS (Korea) cosmetic regulatory information
Korea’s toxic-substance GHS classification: Warning · H400 (category 1) · H410 (category 1)
EU Cosmetics Regulation, Annex III (restricted substances), entry 336
Restriction III/336
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ヘキサメチルインダノピラン: 本品は、次の化学式で表される多環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 1222-05-5
- EC No.EU chemical inventory number
- 214-946-9
- DTXSIDUS EPA chemical ID
- DTXSID8027373
- DTXCIDUS EPA compound ID
- DTXCID607373
- IUPAC
- 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydroindeno[5,6-c]pyran
- Molecular formula
- C18H26O
- Molecular weight
- 258.405 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- -10 ℃
- Initial boiling point and range
- 318 ℃
- Flash point
- &, gt, 100 ℃
- Vapour pressure
- 0.0727 ㎩(25°C)
- Water solubility
- 1.75 ㎎/ℓ
- Relative density
- 0.99~1.015
- n-Octanol/water partition coefficient (Kow)
- 5.99
- Auto-ignition temperature
- 200 ℃
- Viscosity
- 12914 mPa S
- Molecular weight
- 258.41
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 385 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance383
- Deodorizer2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 17%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not classified
Skin Irritation · Screening - Not classified
Skin Sensitization · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Not classified
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU restricted substances (Annex III)
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese