- Korean limit
- 0.1%
How much products actually contain
No product states its amount yet.
Of the products containing it, 1 list it before the 1% line and 3 after it (usually 1% or less).
Products using this ingredient
4 of 4 confirmed · likeliest to carry enough first
Definition
US FDA substance register · UNII 023XA5Z50L · registered name HEXAMIDINE DIISETHIONATE · single chemical substance
Hexamidine Diisethionate is the organic salt that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Restricted
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Taiwan
- Maximum concentration : 0.1%
European Union
- Maximum concentration in ready for use preparation : 0.1%
Source: MFDS (Korea) cosmetic regulatory information
Restriction V/47
Source: EU CosIng ingredient list
Reviewed by CIR: Hexamidine and Hexamidine Diisethionate
Reviewed by CIR: Final Report on the Safety Assessment of Hexamidine and Hexamidine Diisethionate
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ジイセチオン酸ヘキサミジン: 本品は、次の化学式で表される有機塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 659-40-5
- EC No.EU chemical inventory number
- 211-533-5
- DTXSIDUS EPA chemical ID
- DTXSID60984372
- DTXCIDUS EPA compound ID
- DTXCID301764890
- IUPAC
- 4,4'-[Hexane-1,6-diylbis(oxy)]di(benzene-1-carboximidamidium) bis(2-sulfoethan-1-olate)
- Molecular formula
- C24H38N4O10S2
- Molecular weight
- 606.71 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 349.84 ℃
- Flash point
- 5 ℃
- Vapour pressure
- 5.39E-13 ㎜Hg
- Water solubility
- 9.136 ㎎/ℓ
- Vapour density
- 20.94283741801864
- n-Octanol/water partition coefficient (Kow)
- 3.28
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner4
- Preservative2
- Defoamer2
- Biocide1
Source: US EPA CompTox dashboard
Related literature
- Hexamidine salts – applications in skin health and personal care products · 2017
- Overcoming the skin barrier: Enhancement of topical delivery of hexamidine diisethionate · 2014
- Axillary Contact Dermatitis in an Adult Caused by Hexamidine Diisethionate From Baby Wipes Labelled “Pure Water” · 2025
- Hexamidine and Hexamidine Diisethionate · 2023
- A double-blind randomized controlled comparison of APDDR-0901, a novel cosmeceutical formulation, and 0.1% adapalene gel in the treatment of mild-to-moderate acne vulgaris. · 2011
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata